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SCHEMBL6162087

SCHEMBL6162087

CC(C)(C)OC(=O)NC(C)(C)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N1CCC(c2cn(-c3ccccc3)c3ccccc23)CC1

nearest known ligand 0.60

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.53
▸ KMT2A Q03164 1/20 0.53
▸ CTSL P07711 2/20 0.48
▸ CCKAR P32238 1/20 0.48
▸ CTSS P25774 1/20 0.46
▸ CTSK P43235 1/20 0.46
▸ PKM P14618 1/20 0.45
▸ CALCRL Q16602 1/20 0.44
▸ KLK7 P49862 1/20 0.44
▸ FPR2 P25090 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6162094 1.00 MEN1 (0.53) MEN1KMT2ACTSLCCKARCTSS
SCHEMBL6164109 0.89 MEN1 (0.57) MEN1KMT2ACTSLCCKARCTSS
SCHEMBL6161758 0.89 MEN1 (0.57) MEN1KMT2ACTSLCCKARCTSS
SCHEMBL6162460 0.88 CALCRL (0.49) MEN1KMT2APKMCALCRL
SCHEMBL6162452 0.88 CALCRL (0.49) MEN1KMT2APKMCALCRL
Hydrochloric Acid SCHEMBL6162455 0.88 CALCRL (0.48) MEN1KMT2APKMCALCRL
Hydrochloric Acid SCHEMBL6162463 0.88 CALCRL (0.48) MEN1KMT2APKMCALCRL
SCHEMBL6161139 0.83 MEN1 (0.57) MEN1KMT2ACTSLCCKARCTSS
SCHEMBL6161131 0.83 MEN1 (0.57) MEN1KMT2ACTSLCCKARCTSS
SCHEMBL6161560 0.83 MEN1 (0.57) MEN1KMT2ACTSLCCKARCTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0828754-B1 DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE PFIZER (US) 2005-02-02 — — EP disclosed