Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.38 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6155082 | 0.83 | PIK3CD (0.41) | PIK3CDPIK3CAPIK3CBKMT2AMEN1 | |
| SCHEMBL5557652 | 0.80 | MRGPRX4 (0.43) | KMT2AMEN1LMNAALDH1A1ROCK2 | |
| SCHEMBL5557342 | 0.79 | KMT2A (0.47) | KMT2AMEN1MAPTNPSR1LMNA | |
| SCHEMBL6155089 | 0.79 | PIK3CD (0.48) | PIK3CDPIK3CAPIK3CBKMT2AMEN1 | |
| SCHEMBL5558769 | 0.79 | MAPT (0.46) | KMT2AMEN1MAPTNPSR1LMNA | |
| SCHEMBL5552796 | 0.78 | MAPT (0.42) | KMT2AMEN1MAPTNPSR1LMNA | |
| SCHEMBL6156893 | 0.78 | KMT2A (0.40) | PIK3CDPIK3CAPIK3CBKMT2AMEN1 | |
| SCHEMBL6154208 | 0.77 | HDAC6 (0.40) | PIK3CDPIK3CAPIK3CBKMT2AMEN1 | |
| SCHEMBL6154206 | 0.77 | HDAC6 (0.40) | PIK3CDPIK3CAPIK3CBKMT2AMEN1 | |
| Ammonia Solution, Strong SCHEMBL6155214 | 0.77 | HDAC6 (0.40) | PIK3CDPIK3CAPIK3CBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050065118-A1 | Organosulfur inhibitors of tyrosine phosphatases | METABASIS THERAPEUTICS, INC. | 2005-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065118-A1 | Organosulfur inhibitors of tyrosine phosphatases | PTPRS, PTPRJ, PTPRCAP | PIK3CD 2104/4885PIK3CA 2270/4885PIK3CB 1188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.