Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | STK10 | O94804 | 1/20 | 0.37 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.37 |
| ▸ | GUSB | P08236 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.34 |
| ▸ | UBA2 | Q9UBT2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6678337 | 0.86 | PPARG (0.38) | MAPTHSD11B1PPARGPPARACDK2 | |
| SCHEMBL6162257 | 0.78 | PIK3CD (0.40) | KMT2AMEN1MAPTLMNANPSR1 | |
| SCHEMBL6154206 | 0.77 | HDAC6 (0.40) | KMT2AMEN1MAPTLMNANPSR1 | |
| SCHEMBL6154208 | 0.77 | HDAC6 (0.40) | KMT2AMEN1MAPTLMNANPSR1 | |
| Ammonia Solution, Strong SCHEMBL6155214 | 0.76 | HDAC6 (0.40) | KMT2AMEN1MAPTLMNANPSR1 | |
| SCHEMBL6678334 | 0.69 | HTR7 (0.37) | NPC1RAB9ASMN1; SMN2HPGDHSD11B1 | |
| SCHEMBL12336520 | 0.67 | PIK3CD (0.56) | KMT2AMEN1MAPTPIK3CDPIK3CA | |
| SCHEMBL1346769 | 0.66 | KDR (0.47) | KMT2AMEN1MAPTNPSR1PIK3CD | |
| SCHEMBL9656308 | 0.66 | HSD11B1 (0.47) | NPC1RAB9AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL6157387 | 0.65 | ROCK2 (0.52) | KMT2AMEN1MAPTLMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050065118-A1 | Organosulfur inhibitors of tyrosine phosphatases | METABASIS THERAPEUTICS, INC. | 2005-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065118-A1 | Organosulfur inhibitors of tyrosine phosphatases | PTPRS, PTPRJ, PTPRCAP | KMT2A 875/4885MEN1 4329/4885MAPT 3318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.