Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 1/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28884365 | 0.85 | POLB (0.58) | SLC1A2RIPK1ALDH1A1TSHRMAPT | |
| SCHEMBL4429916 | 0.78 | MAOB (0.55) | PPARGPPARAALDH1A1MAPTMEN1 | |
| SCHEMBL4429913 | 0.78 | MAOB (0.55) | PPARGPPARAALDH1A1MAPTMEN1 | |
| SCHEMBL14643369 | 0.76 | SMN1; SMN2 (0.50) | SLC1A2RIPK1PPARGPPARAALDH1A1 | |
| SCHEMBL2910863 | 0.74 | SLC1A2 (0.59) | SLC1A2RIPK1ALDH1A1TSHRMAPT | |
| SCHEMBL4422878 | 0.74 | ALDH1A1 (0.46) | ALDH1A1TSHRMAPTHPGDMEN1 | |
| SCHEMBL4428660 | 0.74 | ALDH1A1 (0.46) | ALDH1A1TSHRMAPTHPGDMEN1 | |
| SCHEMBL2905073 | 0.74 | SLC1A2 (0.65) | SLC1A2RIPK1ALDH1A1TSHRMAPT | |
| SCHEMBL1397059 | 0.73 | RIPK1 (0.55) | SLC1A2RIPK1ALDH1A1TSHRMAPT | |
| SCHEMBL27472283 | 0.73 | RIPK1 (0.55) | SLC1A2RIPK1ALDH1A1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1517680-A1 | BENZOIC ACID DERIVATIVES AS MODULATORS OF PPAR ALPHA AND GAMMA | Astrazeneca AB (SE) | 2005-03-30 | — | — | EP | disclosed |
| WO-2004000295-A1 | BENZOIC ACID DERIVATIVES AS MODULATORS OF PPAR ALPHA AND GAMMA | ASTRAZENECA AB (SE) | 2003-12-31 | — | — | WO | disclosed |