Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL6162340

Cc1ccc(S(=O)(=O)NC2CCN(C(=O)C(COCc3ccccc3)NC(=O)C(C)(C)N)C2)cc1.O=C(O)C(F)(F)F

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GHSR Q92847 4/20 0.49
F13A1 P00488 2/20 0.43
TGM2 P21980 2/20 0.43
TGM1 P22735 2/20 0.43
HPN P05981 1/20 0.43
ST14 Q9Y5Y6 1/20 0.43
CYP3A4 P08684 2/20 0.43
UGCG Q16739 2/20 0.43
KMT2A Q03164 1/20 0.42
CCKBR P32239 2/20 0.42
F2 P00734 2/20 0.41
TMPRSS6 Q8IU80 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL6161932 1.00 GHSR (0.49) GHSRF13A1TGM2TGM1HPN
SCHEMBL6160771 0.96 GHSR (0.52) GHSRF13A1TGM2TGM1HPN
SCHEMBL6160765 0.96 GHSR (0.52) GHSRF13A1TGM2TGM1HPN
SCHEMBL6161113 0.85 P2RX7 (0.43) GHSRF13A1TGM2TGM1HPN
SCHEMBL6161111 0.85 P2RX7 (0.43) GHSRF13A1TGM2TGM1HPN
Trifluoroacetic Acid SCHEMBL6165608 0.83 GHSR (0.51) GHSRCYP3A4UGCGCCKBR
Trifluoroacetic Acid SCHEMBL6161144 0.83 GHSR (0.51) GHSRCYP3A4UGCGCCKBR
Trifluoroacetic Acid SCHEMBL6165597 0.83 GHSR (0.51) GHSRCYP3A4UGCGCCKBR
Trifluoroacetic Acid SCHEMBL6160638 0.82 GHSR (0.48) GHSRCYP3A4UGCGCCKBR
Trifluoroacetic Acid SCHEMBL6160642 0.82 GHSR (0.48) GHSRCYP3A4UGCGCCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0828754-B1 DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE PFIZER (US) 2005-02-02 EP claimed
EP-0828754-B1 DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE PFIZER (US) 2005-02-02 EP disclosed