Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7725192 | 1.00 | LMNA (0.54) | LMNAMAPK1LTA4HMCHR1DRD2 | |
| SCHEMBL6158965 | 0.84 | SLC6A4 (0.56) | LMNAMAPK1LTA4HDRD2GAA | |
| SCHEMBL6158956 | 0.84 | SLC6A4 (0.56) | LMNAMAPK1LTA4HDRD2GAA | |
| SCHEMBL6160208 | 0.84 | HRH3 (0.49) | LMNAMAPK1MCHR1DRD2GAA | |
| SCHEMBL6160199 | 0.84 | HRH3 (0.49) | LMNAMAPK1MCHR1DRD2GAA | |
| SCHEMBL18171324 | 0.80 | SIGMAR1 (0.68) | LMNAMAPK1LTA4HGAATSHR | |
| SCHEMBL18171325 | 0.80 | SIGMAR1 (0.68) | LMNAMAPK1LTA4HGAATSHR | |
| SCHEMBL3888713 | 0.80 | MCHR1 (0.51) | LMNAMAPK1LTA4HMCHR1DRD2 | |
| SCHEMBL11838011 | 0.78 | SMN1; SMN2 (0.58) | LMNAMAPK1LTA4HDRD2GAA | |
| SCHEMBL7725197 | 0.77 | MCHR1 (0.51) | LMNAMAPK1MCHR1GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755923-B1 | Ameliorant or remedy for symptoms caused by Ischemic diseases and Phenylpiperidine compounds useful therefor | DAIICHI SUNTORY PHARMA CO LTD (JP) | 2005-05-04 | — | — | EP | disclosed |
| US-6469010-B1 | COMPOSITION ALSO FOR ALLEVIATION OR TREATMENT OF SYMPTOMS DERIVED FROM SEIZURES, EPILEPSY AND MIGRAINE HEADACHES, AND SUPPRESSION OF CALCIUM ION OVERLOAD | SUNTORY LIMITED (JP) | 2002-10-22 | — | — | US | disclosed |
| US-6048876-A | ANTICONVULSANTS; ANTIEPILEPIC AGENT | SUNTORY LIMITED (JP) | 2000-04-11 | — | — | US | disclosed |
| EP-0755923-A1 | AMELIORANT OR REMEDY FOR SYMPTOMS CAUSED BY ISCHEMIC DISEASES AND COMPOUNDS USEFUL THEREFOR | SUNTORY LIMITED (JP) | 1997-01-29 | — | — | EP | disclosed |