Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.65 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | ROS1 | P08922 | 1/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19519991 | 1.00 | ELANE (0.65) | ELANEMAOAMAOBCYP2A6TDP1 | |
| SCHEMBL1134729 | 0.91 | MAOA (0.55) | ELANEMAOAMAOBCYP2A6TDP1 | |
| SCHEMBL1134706 | 0.91 | MAOA (0.55) | ELANEMAOAMAOBCYP2A6TDP1 | |
| SCHEMBL546782 | 0.88 | ELANE (0.87) | ELANEMAOAMAOBTDP1ALDH1A1 | |
| SCHEMBL16656188 | 0.88 | ELANE (0.79) | ELANEMAOAMAOBALDH1A1KDM4E | |
| SCHEMBL8987695 | 0.88 | ELANE (0.54) | ELANEMAOAMAOBCYP2A6TDP1 | |
| SCHEMBL17899750 | 0.88 | ELANE (0.87) | ELANEMAOAMAOBTDP1ALDH1A1 | |
| SCHEMBL27462626 | 0.86 | ELANE (0.57) | ELANEMAOAMAOBCYP2A6TDP1 | |
| SCHEMBL10433952 | 0.85 | ELANE (0.56) | ELANEMAOAMAOBTDP1ALDH1A1 | |
| SCHEMBL17882318 | 0.84 | ACVR1 (0.59) | ELANEMAOAMAOBALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0893442-B1 | LYMPH-ABSORBABLE IMIDAZOLE DERIVATIVES | SHIONOGI & CO (JP) | 2005-01-12 | — | — | EP | claimed |
| US-4551502-A | Macromolecular complexes of amidocarbonylic water-soluble polymers and square platinous and equivalent organometallics | HOWELL BOBBY A | 1985-11-05 | — | — | US | disclosed |
| US-4110472-A | CEREBROVASCULAR INSUFFICIENCY, PSYCHOSTIMULATION | BAYER AKTIENGESELLSCHAFT (DE) | 1978-08-29 | — | — | US | disclosed |