Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.62 |
| ▸ | TACR1 | P25103 | 2/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Normeperidine SCHEMBL27449404 | 0.86 | OPRM1 (0.85) | OPRM1OPRD1OPRK1 | |
| SCHEMBL27915147 | 0.82 | OPRM1 (0.55) | OPRM1OPRD1OPRK1 | |
| Trifluoroacetic Acid SCHEMBL8338850 | 0.82 | OPRM1 (0.60) | OPRM1TACR1OPRD1OPRK1 | |
| SCHEMBL7326235 | 0.78 | OPRM1 (0.56) | OPRM1 | |
| Normeperidine SCHEMBL341796 | 0.77 | OPRM1 (1.00) | OPRM1OPRD1OPRK1 | |
| Trifluoroacetic Acid SCHEMBL16413809 | 0.77 | OPRM1 (0.50) | OPRM1TACR1 | |
| SCHEMBL16104359 | 0.77 | DDB1 (0.54) | OPRM1TACR1 | |
| Normeperidine SCHEMBL4537496 | 0.76 | OPRM1 (0.97) | OPRM1OPRD1OPRK1 | |
| Normeperidine SCHEMBL8177568 | 0.76 | OPRM1 (0.97) | OPRM1OPRD1OPRK1 | |
| Normeperidine SCHEMBL4540908 | 0.76 | OPRM1 (0.97) | OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | disclosed |
| US-5936089-A | PIPERIDINE DERIVATIVES; BONE DISORDERS; OBESITY; AGING; CACHEXIA ASSOCIATED WITH AIDS AND CANCER | PFIZER INC (US) | 1999-08-10 | — | — | US | disclosed |
| EP-0828754-A1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER INC. (US) | 1998-03-18 | — | — | EP | disclosed |
| WO-1996038471-A1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER INC. (US) | 1996-12-05 | — | — | WO | disclosed |
| WO-1996035713-A1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER, INC. (US) | 1996-11-14 | — | — | WO | disclosed |