Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6162717 | 0.78 | OPRM1 (0.62) | OPRM1 | |
| SCHEMBL7327775 | 0.78 | OPRM1 (0.43) | OPRM1 | |
| SCHEMBL26130614 | 0.74 | DDB1 (0.52) | OPRM1 | |
| SCHEMBL21873955 | 0.73 | MEN1 (0.41) | — | |
| Normeperidine SCHEMBL341796 | 0.73 | OPRM1 (1.00) | OPRM1 | |
| SCHEMBL5213485 | 0.73 | DDB1 (0.51) | OPRM1 | |
| SCHEMBL16104359 | 0.72 | DDB1 (0.54) | OPRM1 | |
| SCHEMBL27915147 | 0.72 | OPRM1 (0.55) | OPRM1 | |
| Normeperidine SCHEMBL4537496 | 0.72 | OPRM1 (0.97) | OPRM1 | |
| Normeperidine SCHEMBL8177568 | 0.72 | OPRM1 (0.97) | OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376506-B1 | REACTING SULFAMOYL OXAZOLIDONE WITH (1,2,3,4)-TETRAHYDRO-BETA-CARBOLINE TO FORM INHIBITOR; USED TO TREAT ARTHRITIS, OSTEOPOROSIS, PERIODONTAL DISEASE, CARDIOVASCULAR DISEASES, MULTIPLE SCLEROSIS, AND TUMORS | SYNTEX (U.S.A.) LLC | 2002-04-23 | — | — | US | disclosed |
| US-6130220-A | ENZYME INHIBITORS | SYNTEX (USA) INC. (US) | 2000-10-10 | — | — | US | disclosed |