SCHEMBL6162777

SCHEMBL6162777

CCCCOC(OCC)C(C)[O]

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.35
OPRM1 P35372 1/20 0.34
CYP3A4 P08684 1/20 0.33
TP53 P04637 1/20 0.32
DNM1 Q05193 1/20 0.32
ALDH1A1 P00352 1/20 0.32
ADRB2 P07550 1/20 0.32
ADRB1 P08588 1/20 0.32
ADRB3 P13945 1/20 0.32
FAAH O00519 3/20 0.32
CNR1 P21554 1/20 0.32
CNR2 P34972 1/20 0.32
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
THRB P10828 1/20 0.31
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6164958 0.86 LMNA (0.38) LMNATHRB
SCHEMBL6166563 0.83 LMNA (0.47) LMNATHRB
SCHEMBL2949936 0.78 CYP3A4 (0.36) LMNACYP3A4DNM1ALDH1A1ADRB2
SCHEMBL9393419 0.75 ADRB2 (0.45) LMNACYP3A4DNM1ALDH1A1ADRB2
SCHEMBL3579303 0.75 CYP3A4 (0.37) LMNACYP3A4DNM1ALDH1A1ADRB2
SCHEMBL9875264 0.75 CYP3A4 (0.37) CYP3A4DNM1ALDH1A1ADRB2ADRB1
SCHEMBL430719 0.74
SCHEMBL8859199 0.74
SCHEMBL7791270 0.74 ADRB2 (0.39) LMNAOPRM1CYP3A4DNM1ALDH1A1
SCHEMBL27856757 0.72 CYP3A4 (0.41) LMNACYP3A4DNM1ALDH1A1ADRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1055712-B1 Aqueous ink for ink jet recording MITSUI CHEMICALS INC (JP) 2005-02-16 EP disclosed
EP-0818512-B1 Quinoline derivative and use of same MITSUI CHEMICALS INC (JP) 2002-10-02 EP disclosed
US-6407242-B1 REACTING A PHTHALIMIDE COMPOUND WITH A QUINOLINE COMPOUND;ELECTROLUMINESCENCE MITSUI CHEMICALS, INC. (JP) 2002-06-18 US disclosed
EP-1055712-A2 Aqueous ink for ink jet recording Mitsui Chemicals, Inc. (JP) 2000-11-29 EP disclosed
US-6132640-A ZINC COMPLEXES OF QUINOLINE MITSUI CHEMICALS, INC. (JP) 2000-10-17 US disclosed
EP-0818512-A1 Quinoline derivative and use of same MITSUI TOATSU CHEMICALS, Inc. (JP) 1998-01-14 EP disclosed