Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.40 |
| ▸ | MIF | P14174 | 4/20 | 0.36 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluorobenzene SCHEMBL28841539 | 0.84 | — | — | |
| Isothiocyanate SCHEMBL29167061 | 0.84 | MIF (0.44) | NFE2L2MIFPLA2G1BATG4BNPC1 | |
| Fluorobenzene SCHEMBL9630082 | 0.82 | NFE2L2 (0.40) | NFE2L2ALDH1A1HPGDKCNN4NPC1 | |
| Fluorobenzene SCHEMBL20558451 | 0.82 | NFE2L2 (0.40) | NFE2L2ALDH1A1HPGDKCNN4NPC1 | |
| Fluorobenzene SCHEMBL15544432 | 0.80 | NFE2L2 (0.53) | NFE2L2NOX1ALDH1A1MAPTKCNN4 | |
| SCHEMBL22526495 | 0.80 | NFE2L2 (0.53) | NFE2L2NOX1ALDH1A1MAPTKCNN4 | |
| Fluorobenzene SCHEMBL14012524 | 0.80 | — | — | |
| Fluorobenzene SCHEMBL12363 | 0.80 | — | — | |
| Fluorobenzene SCHEMBL7024891 | 0.80 | — | — | |
| Fluorobenzene SCHEMBL27957654 | 0.80 | NFE2L2 (0.53) | NFE2L2NOX1ALDH1A1MAPTKCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116947780-B | Preparation method of thiazolidine-4-thioketone derivative | 华侨大学 | 2025-06-03 | — | — | CN | claimed |
| CN-116947780-A | Preparation method of thiazolidine-4-thioketone derivative | 华侨大学 | 2023-10-27 | — | — | CN | claimed |
| CN-116947780-B | Preparation method of thiazolidine-4-thioketone derivative | 华侨大学 | 2025-06-03 | — | — | CN | disclosed |
| CN-119591559-A | Method for constructing iminothiazole derivative by promoting denitrification of 1,2, 3-triazole by alkali | 昆明理工大学 | 2025-03-11 | — | — | CN | disclosed |
| CN-118515686-B | Antitumor compound, composition and application thereof | 香港大学深圳医院 | 2025-01-21 | — | — | CN | disclosed |
| CN-118515686-A | Antitumor compound, composition and application thereof | 香港大学深圳医院 | 2024-08-20 | — | — | CN | disclosed |
| CN-117623987-A | Isothiocyanate liquid crystal compound containing 2, 5-difluoro substituted benzene and synthesis method | 西安近代化学研究所 | 2024-03-01 | — | — | CN | disclosed |
| CN-117384150-A | Thiazolidinones immunoproteasome inhibitor and its preparation method and pharmaceutical use | 中国医学科学院药物研究所 | 2024-01-12 | — | — | CN | disclosed |
| CN-112079830-B | Inhibitor containing fused ring derivative, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-116947780-A | Preparation method of thiazolidine-4-thioketone derivative | 华侨大学 | 2023-10-27 | — | — | CN | disclosed |
| CN-113292443-B | Process for producing amides | 长沙理工大学 | 2022-07-19 | — | — | CN | disclosed |
| CN-103923078-A | 3,4-disubstituted(1H-pyrazole[3,4-b]pyridine) compound and use thereof | UNIV EAST CHINA SCIENCE & TECH | 2014-07-16 | — | — | CN | disclosed |
| CN-102395567-A | Triazole and imidazole derivatives for use as tgr5 agonists in the treatment of diabetes and obesity | EXELIXIS INC | 2012-03-28 | — | — | CN | disclosed |
| CN-1914173-A | Quinolines useful in treating cardiovascular disease | WYETH CORP (US) | 2007-02-14 | — | — | CN | disclosed |
| EP-1224165-B1 | NOVEL COMPOUNDS | NEW PHARMA RES SWEDEN AB (SE) | 2005-12-14 | — | — | EP | disclosed |
| CN-1205468-C | Method and reagents for quantification of solid-phase reactions using fluorine NMR | AVENTISS PHARMACEUTICAL PRODUC (US) | 2005-06-08 | — | — | CN | disclosed |
| US-6875764-B1 | Urea and thiourea compounds useful for treatment of coccidiosis | NEW PHARMA RESEARCH SWEDEN AB (SE) | 2005-04-05 | — | — | US | disclosed |
| EP-1224165-A1 | NOVEL COMPOUNDS | New Pharma Research Sweden AB (SE) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001030749-A1 | NOVEL COMPOUNDS | NEW PHARMA RESEARCH SWEDEN AB (SE) | 2001-05-03 | — | — | WO | disclosed |
| CN-1284165-A | Method and reagents for quantification of solid-phase reactions using fluorine NMR | AVENTISS PHARMACEUTICAL PRODUC (US) | 2001-02-14 | — | — | CN | disclosed |