Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.40 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALPG | P10696 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.32 |
| ▸ | BAD | Q92934 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluorobenzene SCHEMBL9630082 | 1.00 | NFE2L2 (0.40) | NFE2L2KCNN4NPC1RAB9APKM | |
| Fluorobenzene SCHEMBL11680297 | 0.95 | NFE2L2 (0.37) | NFE2L2KCNN4NPC1RAB9APKM | |
| Fluorobenzene SCHEMBL28813818 | 0.88 | NFE2L2 (0.43) | NFE2L2KCNN4NPC1RAB9APKM | |
| SCHEMBL27644939 | 0.84 | CES2 (0.43) | KCNN4NPC1RAB9AALDH1A1BCL2L1 | |
| Fluorobenzene SCHEMBL6162846 | 0.82 | NFE2L2 (0.40) | NFE2L2KCNN4NPC1RAB9AHPGD | |
| Fluorobenzene SCHEMBL7024891 | 0.80 | — | — | |
| SCHEMBL22526495 | 0.80 | NFE2L2 (0.53) | NFE2L2KCNN4NPC1RAB9AALDH1A1 | |
| Fluorobenzene SCHEMBL14012524 | 0.80 | — | — | |
| Fluorobenzene SCHEMBL12363 | 0.80 | — | — | |
| Fluorobenzene SCHEMBL15544432 | 0.80 | NFE2L2 (0.53) | NFE2L2KCNN4NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117525585-A | Low-temperature electrolyte of lithium ion battery and lithium ion battery | 合肥乾锐科技有限公司 | 2024-02-06 | — | — | CN | claimed |
| CN-107488146-B | Isocorydine derivative and preparation method and application thereof | 中国科学院兰州化学物理研究所 | 2020-05-22 | — | — | CN | claimed |
| EP-3403651-B1 | ISOCORYDINE DERIVATIVES, PREPARATION METHOD AND USE THEREOF | LANZHOU INST CHEMICAL PHYSICS CAS (CN) | 2019-10-30 | — | — | EP | claimed |
| US-20180334448-A1 | Isocorydine derivatives, preparation method and use thereof | LANZHOU INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY OF SCIENCES (CN) | 2018-11-22 | — | — | US | claimed |
| EP-3403651-A1 | ISOCORYDINE DERIVATIVES, PREPARATION METHOD AND USE THEREOF | Lanzhou Institute Of Chemical Physics Chinese Academy of Sciences (CN) | 2018-11-21 | — | — | EP | claimed |
| CN-107488146-A | ICD derivative and its preparation method and application | 中国科学院兰州化学物理研究所 | 2017-12-19 | — | — | CN | claimed |
| CN-114380874-B | Macrolide antibiotics, preparation method and application thereof | 中国医学科学院医药生物技术研究所 | 2024-06-21 | — | — | CN | disclosed |
| CN-118221633-A | TRPV1/URAT1 dual inhibitor, preparation method and application thereof | 郑州大学第一附属医院 | 2024-06-21 | — | — | CN | disclosed |
| CN-116082195-B | Pleuromutilin urea compounds, and preparation method and application thereof | 中国医学科学院药物研究所 | 2024-03-26 | — | — | CN | disclosed |
| CN-117525585-A | Low-temperature electrolyte of lithium ion battery and lithium ion battery | 合肥乾锐科技有限公司 | 2024-02-06 | — | — | CN | disclosed |
| CN-117525585-A | Low-temperature electrolyte of lithium ion battery and lithium ion battery | 合肥乾锐科技有限公司 | 2024-02-06 | — | — | CN | disclosed |
| WO-2023236263-A1 | BENZOXAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 苏州大学 | 2023-12-14 | — | — | WO | disclosed |
| CN-116082195-A | Pleuromutilin urea compounds, and preparation method and application thereof | 中国医学科学院药物研究所 | 2023-05-09 | — | — | CN | disclosed |
| CN-1205468-C | Method and reagents for quantification of solid-phase reactions using fluorine NMR | AVENTISS PHARMACEUTICAL PRODUC (US) | 2005-06-08 | — | — | CN | disclosed |
| CN-1478078-A | Nitrogen-containing aromatic ring derivatives | ������������ʽ���� | 2004-02-25 | — | — | CN | disclosed |
| CN-1284165-A | Method and reagents for quantification of solid-phase reactions using fluorine NMR | AVENTISS PHARMACEUTICAL PRODUC (US) | 2001-02-14 | — | — | CN | disclosed |
| CN-1027640-C | Process for producing novel trifluoromethyl ketone substituted peptide derivatives | ICI AMERICA INC (US) | 1995-02-15 | — | — | CN | disclosed |
| CN-87100707-A | Nitrogenous condensed heterocyclic compouds, its preparation method and contain their formula of medicine | — | 1987-09-02 | — | — | CN | disclosed |
| CN-86105597-A | Make the method for novel pyrazoline compounds | — | 1987-02-25 | — | — | CN | disclosed |
| CN-86101066-A | Process for producing novel trifluoromethyl ketone substituted peptide derivatives | — | 1986-11-05 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180334448-A1 | Isocorydine derivatives, preparation method and use thereof | CCND2, CCND3, IDH3A | NFE2L2 928/4885KCNN4 560/4885NPC1 910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.