SCHEMBL6162851

SCHEMBL6162851

CC(=O)C1(c2ccccc2)CCN(C(=O)C(COCc2ccccc2)NC(=O)C(C)(C)N)CC1

nearest known ligand 0.62

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GHSR Q92847 12/20 0.62
UGCG Q16739 2/20 0.47
CYP3A4 P08684 1/20 0.47
TACR1 P25103 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6162855 1.00 GHSR (0.62) GHSRUGCGCYP3A4TACR1
Hydrochloric Acid SCHEMBL6163148 0.99 GHSR (0.62) GHSRUGCGCYP3A4TACR1
Hydrochloric Acid SCHEMBL6164166 0.99 GHSR (0.62) GHSRUGCGCYP3A4TACR1
SCHEMBL27479333 0.94 GHSR (0.63) GHSRUGCGCYP3A4TACR1
SCHEMBL27479332 0.94 GHSR (0.63) GHSRUGCGCYP3A4TACR1
SCHEMBL6165535 0.89 GHSR (0.59) GHSRUGCGCYP3A4
Hydrochloric Acid SCHEMBL6165538 0.89 GHSR (0.58) GHSRUGCGCYP3A4
Hydrochloric Acid SCHEMBL6163586 0.89 GHSR (0.58) GHSRUGCGCYP3A4
SCHEMBL6160742 0.88 GHSR (0.58) GHSRUGCGCYP3A4TACR1
SCHEMBL6160739 0.88 GHSR (0.58) GHSRUGCGCYP3A4TACR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0828754-B1 DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE PFIZER (US) 2005-02-02 EP claimed