Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 6/20 | 0.59 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.48 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | UGCG | Q16739 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6163586 | 0.99 | GHSR (0.58) | GHSROPRM1OPRD1OPRK1SLC22A1 | |
| Hydrochloric Acid SCHEMBL6165538 | 0.99 | GHSR (0.58) | GHSROPRM1OPRD1OPRK1SLC22A1 | |
| SCHEMBL27479333 | 0.90 | GHSR (0.63) | GHSRCYP3A4UGCG | |
| SCHEMBL27479332 | 0.90 | GHSR (0.63) | GHSRCYP3A4UGCG | |
| SCHEMBL6162851 | 0.89 | GHSR (0.62) | GHSRCYP3A4UGCG | |
| SCHEMBL6162855 | 0.89 | GHSR (0.62) | GHSRCYP3A4UGCG | |
| Hydrochloric Acid SCHEMBL6164166 | 0.89 | GHSR (0.62) | GHSRCYP3A4UGCG | |
| Hydrochloric Acid SCHEMBL6163148 | 0.89 | GHSR (0.62) | GHSRCYP3A4UGCG | |
| SCHEMBL6163155 | 0.87 | GHSR (0.46) | GHSROPRM1OPRD1OPRK1SLC22A1 | |
| Hydrochloric Acid SCHEMBL6162389 | 0.86 | GHSR (0.57) | GHSRCYP3A4UGCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | claimed |
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | disclosed |
| US-5936089-A | PIPERIDINE DERIVATIVES; BONE DISORDERS; OBESITY; AGING; CACHEXIA ASSOCIATED WITH AIDS AND CANCER | PFIZER INC (US) | 1999-08-10 | — | — | US | disclosed |
| WO-1996035713-A1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER, INC. (US) | 1996-11-14 | — | — | WO | disclosed |