Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.34 |
| ▸ | DRD3 | P35462 | 8/20 | 0.34 |
| ▸ | DRD1 | P21728 | 5/20 | 0.34 |
| ▸ | DRD4 | P21917 | 5/20 | 0.34 |
| ▸ | DRD5 | P21918 | 5/20 | 0.34 |
| ▸ | HTR1D | P28221 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12354193 | 0.97 | DRD2 (0.34) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL19141072 | 0.86 | — | — | |
| SCHEMBL28881160 | 0.84 | DRD2 (0.32) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL17395579 | 0.83 | — | — | |
| SCHEMBL8388405 | 0.81 | RXRA (0.30) | — | |
| SCHEMBL5668749 | 0.81 | — | — | |
| SCHEMBL7384939 | 0.78 | DRD2 (0.31) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL12616336 | 0.78 | HTR2C (0.33) | DRD2DRD3HTR1D | |
| SCHEMBL25317898 | 0.74 | DRD2 (0.32) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL2754407 | 0.74 | DRD2 (0.31) | DRD2DRD3DRD1DRD4DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154282-A1 | COMPOUNDS HAVING A T-STRUCTURE FORMED BY AT LEAST FOUR CYCLES FOR USE IN THE TREATMENT OF CANCER AND OTHER INDICATIONS | THERAS, INC. (US) | 2023-08-17 | — | — | WO | disclosed |
| EP-1254136-A4 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG CHEM INVESTMENT LTD (KR) | 2005-06-01 | — | — | EP | disclosed |
| EP-1254136-A1 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG Chem Investment, Ltd. (KR) | 2002-11-06 | — | — | EP | disclosed |
| WO-2001055146-A1 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG CHEM INVESTMENT LTD. (KR) | 2001-08-02 | — | — | WO | disclosed |