SCHEMBL616338

SCHEMBL616338

Fc1c(F)c(F)c(-c2cccs2)c(F)c1F

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 2/20 0.43
MAPT P10636 5/20 0.43
KDM4E B2RXH2 4/20 0.43
MEN1 O00255 2/20 0.43
HPGD P15428 2/20 0.43
KMT2A Q03164 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
ALDH1A1 P00352 2/20 0.43
ACHE P22303 1/20 0.42
TYMP P19971 1/20 0.40
CYP3A4 P08684 2/20 0.39
CYP2C9 P11712 2/20 0.39
LTA4H P09960 2/20 0.39
CYP2E1 P05181 1/20 0.39
CYP2A6 P11509 1/20 0.39
CYP2B6 P20813 1/20 0.39
HSD17B10 Q99714 3/20 0.38
POLB P06746 2/20 0.38
ALOX15 P16050 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6744117 0.97 MAPT (0.44) DHODHMAPTKDM4EMEN1HPGD
SCHEMBL12608072 0.87 DPP4 (0.47) DHODHMAPTKDM4EMEN1HPGD
SCHEMBL7040112 0.87 DHODH (0.40) DHODHMAPTKDM4EMEN1HPGD
SCHEMBL8152470 0.84 MAPT (0.41) DHODHMAPTKDM4EMEN1HPGD
SCHEMBL1816522 0.84 HSD17B10 (0.42) DHODHMAPTKDM4EMEN1HPGD
SCHEMBL18267383 0.83 DHODH (0.47) DHODHMAPTKDM4EMEN1HPGD
SCHEMBL7135870 0.81 MAPT (0.52) MAPTKDM4EMEN1HPGDKMT2A
SCHEMBL9976521 0.81 ACHE (0.40) DHODHMAPTKDM4EMEN1HPGD
SCHEMBL726615 0.79 DHODH (0.41) DHODHMAPTKDM4EMEN1HPGD
SCHEMBL5227411 0.78 MAPT (0.46) DHODHMAPTKDM4EMEN1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115895327-B Display screen functional film and preparation method and application thereof 广东省科学院化工研究所 2024-01-05 CN claimed
EP-0277194-B1 OLEFIN OLIGOMERIZATION PROCESS AND CATALYST CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1992-01-02 EP claimed
EP-0277194-A4 OLEFIN OLIGOMERIZATION PROCESS AND CATALYST. CHEVRON RES (US) 1988-11-23 EP claimed
EP-0277194-A1 OLEFIN OLIGOMERIZATION PROCESS AND CATALYST. CHEVRON RES (US) 1988-08-10 EP claimed
US-4757042-A Complex of nickel and palladium with fluoroorganic thiol or sulfide ligand and borohydride or organoaluminum halide or alkoxide CHEVRON RESEARCH COMPANY (US) 1988-07-12 US claimed
WO-1988001261-A1 OLEFIN OLIGOMERIZATION PROCESS AND CATALYST CHEVRON RESEARCH COMPANY (US) 1988-02-25 WO claimed
US-4677241-A USING TRANSITION METAL COMPLEX CATALYST AND ORGANOMETALLIC REDUCING AGENT CHEVRON RESEARCH COMPANY (US) 1987-06-30 US claimed
CN-119866458-A Polyfluoroaromatic derivatives for liquid lenses 康宁股份有限公司 2025-04-22 CN disclosed
US-20250002519-A1 NOVEL PRECATALYST SCAFFOLDS FOR CROSS-COUPLING REACTIONS, AND METHODS OF MAKING AND USING SAME UNIV YALE (US) 2025-01-02 US disclosed
US-12071445-B2 Precatalyst scaffolds for cross-coupling reactions, and methods of making and using same YALE UNIVERSITY (US) 2024-08-27 US disclosed
CN-118222288-A PtAg alloy nanocluster and preparation method and application thereof 安徽大学 2024-06-21 CN disclosed
CN-115233442-B Fabric sheet 朴洪旭 2024-03-01 CN disclosed
CN-115895327-B Display screen functional film and preparation method and application thereof 广东省科学院化工研究所 2024-01-05 CN disclosed
WO-2003010778-A1 n-TYPE THIOPHENE SEMICONDUCTORS NORTHWESTERN UNIVERSITY (US) 2003-02-06 WO disclosed
EP-0277194-B1 OLEFIN OLIGOMERIZATION PROCESS AND CATALYST CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1992-01-02 EP disclosed
EP-0277194-A4 OLEFIN OLIGOMERIZATION PROCESS AND CATALYST. CHEVRON RES (US) 1988-11-23 EP disclosed
EP-0277194-A1 OLEFIN OLIGOMERIZATION PROCESS AND CATALYST. CHEVRON RES (US) 1988-08-10 EP disclosed
US-4757042-A Complex of nickel and palladium with fluoroorganic thiol or sulfide ligand and borohydride or organoaluminum halide or alkoxide CHEVRON RESEARCH COMPANY (US) 1988-07-12 US disclosed
WO-1988001261-A1 OLEFIN OLIGOMERIZATION PROCESS AND CATALYST CHEVRON RESEARCH COMPANY (US) 1988-02-25 WO disclosed
US-4677241-A USING TRANSITION METAL COMPLEX CATALYST AND ORGANOMETALLIC REDUCING AGENT CHEVRON RESEARCH COMPANY (US) 1987-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250002519-A1 NOVEL PRECATALYST SCAFFOLDS FOR CROSS-COUPLING REACTIONS, AND METHODS OF MAKING AND USING SAME TIMCC, YAP1, TET2 DHODH 1721/4885MAPT 3401/4885KDM4E 656/4885
US-12071445-B2 Precatalyst scaffolds for cross-coupling reactions, and methods of making and using same TIMCC, YAP1, TET2 DHODH 1538/4885MAPT 3084/4885KDM4E 844/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.