SCHEMBL6163462

SCHEMBL6163462

Cc1ccc2[nH]c(C(=O)N[C@@H](Cc3ccccc3)C(=O)O)cc2c1

nearest known ligand 0.81

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PYGL P06737 9/20 0.76
CCKAR P32238 1/20 0.62
CCKBR P32239 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6163466 1.00 PYGL (0.76) PYGLCCKARCCKBR
SCHEMBL7971407 0.87 CCKAR (0.79) PYGLCCKARCCKBR
SCHEMBL6162503 0.86 PYGL (1.00) PYGL
SCHEMBL6165239 0.86 PYGL (0.78) PYGLCCKARCCKBR
SCHEMBL6160275 0.86 PYGL (0.78) PYGLCCKARCCKBR
SCHEMBL5822796 0.83 TAS1R3 (0.58) PYGL
SCHEMBL13271649 0.83 PYGL (0.65) PYGLCCKARCCKBR
SCHEMBL14845701 0.79 KDM4E (0.72) PYGL
SCHEMBL2106408 0.79 PYGL (0.71) PYGLCCKARCCKBR
SCHEMBL2106407 0.79 PYGL (0.71) PYGLCCKARCCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240067950-A1 MEANS AND METHODS FOR DETOXIFYING OCHRATOXIN A DSM Austria GmbH (AT) 2024-02-29 US disclosed
CN-114645037-A Means and methods for detoxification of ochratoxin A 艾尔柏股份公司 2022-06-21 CN disclosed
EP-1134213-B1 Process for the preparation of substituted N-(indole-2-carbonyl)- glycinamides PFIZER (US) 2005-11-02 EP disclosed
EP-0832065-B1 SUBSTITUTED N-(INDOLE-2-CARBONYL)-GLYCINAMIDES AND DERIVATIVES AS GLYCOGEN PHOSPHORYLASE INHIBITORS PFIZER (US) 2001-10-10 EP disclosed
EP-1134213-A2 Process for the preparation of substituted N-(indole-2-carbonyl)- glycinamides PFIZER INC. (US) 2001-09-19 EP disclosed
US-6277877-B1 GLYCOGEN PHOSPHORYLASE INHIBITOR; ANTIDIABETIC AGENTS PFIZER, INC. 2001-08-21 US disclosed
US-6107329-A HYPOTENSIVE AGENTS; CARDIOVASCULAR DISORDERS PFIZER, INC. (US) 2000-08-22 US disclosed
EP-0832065-A1 SUBSTITUTED N-(INDOLE-2-CARBONYL)-GLYCINAMIDES AND DERIVATIVES AS GLYCOGEN PHOSPHORYLASE INHIBITORS PFIZER INC. (US) 1998-04-01 EP disclosed
WO-1996039384-A1 SUBSTITUTED N-(INDOLE-2-CARBONYL)-GLYCINAMIDES AND DERIVATIVES AS GLYCOGEN PHOSPHORYLASE INHIBITORS PFIZER, INC. (US) 1996-12-12 WO disclosed