Sugi Predict

Sugi Predict / Compounds / SCHEMBL6163554

SCHEMBL6163554

SCHEMBL6163554

CC[CH]SCCCCCCCC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 4/20 0.42
▸ THRB P10828 2/20 0.42
▸ HSD17B10 Q99714 2/20 0.37
▸ CES2 O00748 1/20 0.37
▸ CTSL P07711 1/20 0.37
▸ CTSB P07858 1/20 0.37
▸ GMNN O75496 1/20 0.37
▸ TP53 P04637 1/20 0.37
▸ POLB P06746 1/20 0.37
▸ MAPT P10636 1/20 0.37
▸ CYP2C9 P11712 1/20 0.37
▸ BLM P54132 1/20 0.37
▸ CA2 P00918 1/20 0.35
▸ DNM1 Q05193 5/20 0.35
▸ DEGS1 O15121 1/20 0.34
▸ ASAH1 Q13510 1/20 0.34
▸ ALDH1A1 P00352 2/20 0.33
▸ LMNA P02545 2/20 0.33
▸ KMT2A Q03164 2/20 0.33
▸ HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11529155 1.00 TSHR (0.42) TSHRTHRBHSD17B10CES2CTSL
SCHEMBL9312124 1.00 TSHR (0.42) TSHRTHRBHSD17B10CES2CTSL
SCHEMBL5892193 1.00 TSHR (0.42) TSHRTHRBHSD17B10CES2CTSL
SCHEMBL9312686 1.00 TSHR (0.42) TSHRTHRBHSD17B10CES2CTSL
SCHEMBL5669090 0.97 — —
SCHEMBL1679196 0.89 — —
SCHEMBL199163 0.82 TSHR (0.44) TSHRTHRBHSD17B10CES2CTSL
SCHEMBL199898 0.82 TSHR (0.44) TSHRTHRBHSD17B10CES2CTSL
SCHEMBL201272 0.82 TSHR (0.44) TSHRTHRBHSD17B10CES2CTSL
SCHEMBL199143 0.82 TSHR (0.44) TSHRTHRBHSD17B10CES2CTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1016661-B1 2,6-DICHLORO-4-PYRIDINEMETHANOL DERIVATIVES AS AGRICULTURAL CHEMICALS DAINIPPON INK & CHEMICALS (JP) 2005-08-03 — — EP disclosed
US-6515051-B2 Stability and durability and a low loss rate when incorporated into automotive coatings; soluble in a variety of substrates including thermoplastic polymers and often are colorless CIBA SPECIALTY CHEMICALS CORPORATION 2003-02-04 — — US disclosed
US-6458872-B1 FOR USE IN AUTOMOTIVE COATINGS, THERMOPLASTIC FORMULATIONS CIBA SPECIALTY CHEMICALS CORPORATION 2002-10-01 — — US disclosed
US-20020099221-A1 Benzotriazole UV absorbers having enhanced durability RAVICHANDRAN RAMANATHAN (US) 2002-07-25 — — US disclosed
US-20020065341-A1 Benzotriazole UV absorbers having enhanced durability RAVICHANDRAN RAMANATHAN (US) 2002-05-30 — — US disclosed
US-6281231-B1 2,6-dichloro-4-pyridinemethanol derivatives and agricultural chemicals DAINIPPON INK AND CHEMICAL, INC. (JP) 2001-08-28 — — US disclosed
US-6262151-B1 FOR AUTOMOTIVE COATINGS CIBA SPECIALTY CHEMICALS CORPORATION 2001-07-17 — — US disclosed
US-20010007886-A1 Benzotriazole UV absorbers having enhanced durability RAVICHANDRAN RAMANATHAN (US) 2001-07-12 — — US disclosed
US-6166218-A Benzotriazole UV absorbers having enhanced durability CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-12-26 — — US disclosed
EP-1016661-A1 2,6-DICHLORO-4-PYRIDINEMETHANOL DERIVATIVES AND AGRICULTURAL CHEMICALS DAINIPPON INK AND CHEMICALS, INC. (JP) 2000-07-05 — — EP disclosed
US-5942626-A REACTING A 5-HALO-SUBSTITUTED BENZOTRIAZOLE WITH A MERCAPTO COMPOUND IN THE PRESENCE OF A GROUP 1A METAL OR GROUP 2A COMPOUND FORMING 5-THIO-SUBSTITUTED 2H-BENZOTRIAZOLES HAVING ENHANCED ABSORBANCE AT LONGER WAVELENGTHS CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-08-24 — — US disclosed
US-5516914-A Compositions stabilized with 5-thio-substituted benzotriazole UV-absorbers CIBA-GEIGY CORPORATION (US) 1996-05-14 — — US disclosed
US-5436349-A Photostabilizers for polymers for radiation resistance CIBA-GEIGY CORPORATION (US) 1995-07-25 — — US disclosed
US-5280124-A Having a phenol structure in position 2 CIBA-GEIGY CORPORATION (US) 1994-01-18 — — US disclosed
US-5278314-A N-Phenol-substituted benzotriazoles CIBA-GEIGY CORPORATION (US) 1994-01-11 — — US disclosed
EP-0576527-A1 5-THIO-SUBSTITUTED BENZOTRIAZOLE UV-ABSORBERS AND STABILIZED COMPOSITIONS Ciba SC Holding AG (CH) 1994-01-05 — — EP disclosed
EP-0572554-A1 5-SULFONYL-SUBSTITUTED BENZOTRIAZOLE UV-ABSORBERS AND STABILIZED COMPOSITIONS Ciba SC Holding AG (CH) 1993-12-08 — — EP disclosed
WO-1992014718-A1 5-THIO-SUBSTITUTED BENZOTRIAZOLE UV-ABSORBERS AND STABILIZED COMPOSITIONS CIBA-GEIGY AG (CH) 1992-09-03 — — WO disclosed
WO-1992014717-A1 5-SULFONYL-SUBSTITUTED BENZOTRIAZOLE UV-ABSORBERS AND STABILIZED COMPOSITIONS CIBA-GEIGY AG (CH) 1992-09-03 — — WO disclosed
EP-0042359-B1 PHOSPHONOUS-ACID MONOESTER MONOAMIDE AND ORGANIC POLYMERS STABILIZED THEREWITH CIBA-GEIGY AG (CH) 1984-10-31 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020099221-A1 Benzotriazole UV absorbers having enhanced durability TERT, AHR, ARNT TSHR 1157/4885THRB 800/4885HSD17B10 1689/4885
US-20020065341-A1 Benzotriazole UV absorbers having enhanced durability TERT, AHR, ARNT TSHR 1157/4885THRB 800/4885HSD17B10 1689/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.