Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | CCKBR | P32239 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6163589 | 1.00 | KMT2A (0.49) | KMT2ACCKBRMAPK1NPSR1PABPC1 | |
| Hydrochloric Acid SCHEMBL6161523 | 0.86 | GHSR (0.53) | KMT2ACCKBRNPSR1EPHX2MEN1 | |
| Hydrochloric Acid SCHEMBL6161521 | 0.86 | GHSR (0.53) | KMT2ACCKBRNPSR1EPHX2MEN1 | |
| SCHEMBL6162935 | 0.84 | PPARA (0.48) | KMT2ACCKBRMAPK1PPARA | |
| SCHEMBL6162932 | 0.84 | PPARA (0.48) | KMT2ACCKBRMAPK1PPARA | |
| SCHEMBL6163918 | 0.83 | CYP3A4 (0.46) | KMT2ACCKBRMAPK1PPARA | |
| SCHEMBL6163920 | 0.83 | CYP3A4 (0.46) | KMT2ACCKBRMAPK1PPARA | |
| SCHEMBL6161524 | 0.81 | CTSS (0.43) | KMT2ACCKBRMAPK1PPARA | |
| SCHEMBL6162110 | 0.80 | PPARA (0.44) | KMT2ACCKBRMAPK1PPARA | |
| SCHEMBL6162114 | 0.80 | PPARA (0.44) | KMT2ACCKBRMAPK1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | disclosed |
| EP-0828754-A1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER INC. (US) | 1998-03-18 | — | — | EP | disclosed |
| WO-1996038471-A1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER INC. (US) | 1996-12-05 | — | — | WO | disclosed |
| WO-1996035713-A1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER, INC. (US) | 1996-11-14 | — | — | WO | disclosed |