Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.50 |
| ▸ | PLAUR | Q03405 | 4/20 | 0.48 |
| ▸ | MOK | Q9UQ07 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6164221 | 1.00 | TRPV1 (0.50) | TRPV1PLAURMOKMAPTUSP2 | |
| SCHEMBL6165906 | 1.00 | TRPV1 (0.50) | TRPV1PLAURMOKMAPTUSP2 | |
| SCHEMBL6165986 | 0.88 | TRPV1 (0.51) | TRPV1PLAURHCRTR1HCRTR2 | |
| SCHEMBL6167452 | 0.88 | PLAUR (0.48) | TRPV1PLAURPOLBHCRTR1HCRTR2 | |
| SCHEMBL6166185 | 0.88 | PLAUR (0.48) | TRPV1PLAURPOLBHCRTR1HCRTR2 | |
| SCHEMBL6165842 | 0.88 | PLAUR (0.48) | TRPV1PLAURPOLBHCRTR1HCRTR2 | |
| SCHEMBL6163729 | 0.86 | PDE10A (0.60) | TRPV1PLAURPOLBHCRTR1HCRTR2 | |
| SCHEMBL6166464 | 0.86 | PDE10A (0.60) | TRPV1PLAURPOLBHCRTR1HCRTR2 | |
| SCHEMBL6163843 | 0.86 | PDE10A (0.60) | TRPV1PLAURPOLBHCRTR1HCRTR2 | |
| SCHEMBL6161963 | 0.86 | TRPV1 (0.57) | TRPV1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1337523-B1 | 2,4-SUBSTITUTED PYRIDINE DERIVATIVES | NEUROGEN CORP (US) | 2005-10-19 | — | — | EP | claimed |