Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.60 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.49 |
| ▸ | ACACA | Q13085 | 1/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | PLAUR | Q03405 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6163729 | 1.00 | PDE10A (0.60) | PDE10ATRPV1ACACAROCK2PLAUR | |
| SCHEMBL6166464 | 1.00 | PDE10A (0.60) | PDE10ATRPV1ACACAROCK2PLAUR | |
| SCHEMBL6163593 | 0.86 | TRPV1 (0.50) | TRPV1PLAURPOLBHCRTR1HCRTR2 | |
| SCHEMBL6167452 | 0.86 | PLAUR (0.48) | TRPV1PLAURPOLBHCRTR1HCRTR2 | |
| SCHEMBL6166185 | 0.86 | PLAUR (0.48) | TRPV1PLAURPOLBHCRTR1HCRTR2 | |
| SCHEMBL6165842 | 0.86 | PLAUR (0.48) | TRPV1PLAURPOLBHCRTR1HCRTR2 | |
| SCHEMBL6164221 | 0.86 | TRPV1 (0.50) | TRPV1PLAURPOLBHCRTR1HCRTR2 | |
| SCHEMBL6165906 | 0.86 | TRPV1 (0.50) | TRPV1PLAURPOLBHCRTR1HCRTR2 | |
| SCHEMBL6165986 | 0.86 | TRPV1 (0.51) | TRPV1PLAURRAB9AHCRTR1HCRTR2 | |
| SCHEMBL6161963 | 0.83 | TRPV1 (0.57) | PDE10ATRPV1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1337523-B1 | 2,4-SUBSTITUTED PYRIDINE DERIVATIVES | NEUROGEN CORP (US) | 2005-10-19 | — | — | EP | claimed |