Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | PLAUR | Q03405 | 5/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.46 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6164570 | 0.93 | RAB9A (0.48) | TRPV1RAB9APLAURAURKAHCRTR1 | |
| SCHEMBL6162329 | 0.93 | RAB9A (0.48) | TRPV1RAB9APLAURAURKAHCRTR1 | |
| SCHEMBL6162269 | 0.93 | RAB9A (0.48) | TRPV1RAB9APLAURAURKAHCRTR1 | |
| SCHEMBL6165844 | 0.90 | RAB9A (0.50) | TRPV1RAB9APLAURAURKAHCRTR1 | |
| SCHEMBL6163701 | 0.90 | RAB9A (0.50) | TRPV1RAB9APLAURAURKAHCRTR1 | |
| SCHEMBL6167175 | 0.90 | RAB9A (0.50) | TRPV1RAB9APLAURAURKAHCRTR1 | |
| SCHEMBL6167551 | 0.90 | RAB9A (0.49) | TRPV1RAB9APLAURHCRTR1HCRTR2 | |
| SCHEMBL6166225 | 0.90 | RAB9A (0.49) | TRPV1RAB9APLAURHCRTR1HCRTR2 | |
| SCHEMBL6166777 | 0.90 | RAB9A (0.49) | TRPV1RAB9APLAURHCRTR1HCRTR2 | |
| SCHEMBL6164221 | 0.88 | TRPV1 (0.50) | TRPV1PLAURHCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1337523-B1 | 2,4-SUBSTITUTED PYRIDINE DERIVATIVES | NEUROGEN CORP (US) | 2005-10-19 | — | — | EP | claimed |