Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 5/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6163772 | 1.00 | KMT2A (0.43) | KMT2AMEN1MAPK1CCR1MCL1 | |
| SCHEMBL6161237 | 0.86 | CCR1 (0.44) | KMT2AMEN1CCR1 | |
| SCHEMBL6161242 | 0.86 | CCR1 (0.44) | KMT2AMEN1CCR1 | |
| Hydrochloric Acid SCHEMBL6159712 | 0.85 | CCR1 (0.43) | KMT2AMEN1CCR1 | |
| Hydrochloric Acid SCHEMBL6163321 | 0.85 | CCR1 (0.43) | KMT2AMEN1CCR1 | |
| SCHEMBL6162595 | 0.85 | CALCRL (0.51) | — | |
| SCHEMBL6162588 | 0.85 | CALCRL (0.51) | — | |
| SCHEMBL6160719 | 0.83 | ACE (0.46) | KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6160724 | 0.83 | ACE (0.46) | KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6162859 | 0.82 | CTSS (0.49) | KMT2AMEN1MAPK1CCR1PABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | disclosed |
| US-5936089-A | PIPERIDINE DERIVATIVES; BONE DISORDERS; OBESITY; AGING; CACHEXIA ASSOCIATED WITH AIDS AND CANCER | PFIZER INC (US) | 1999-08-10 | — | — | US | disclosed |