Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL460544 | 0.77 | GAA (0.36) | — | |
| SCHEMBL15973038 | 0.77 | — | — | |
| SCHEMBL538532 | 0.71 | TNKS2 (0.42) | GSK3BTNKS2 | |
| SCHEMBL13066286 | 0.63 | ADRA2A (0.37) | GSK3B | |
| SCHEMBL12895008 | 0.62 | GSK3B (0.39) | GSK3BTNKS2 | |
| SCHEMBL450139 | 0.61 | — | — | |
| SCHEMBL4183810 | 0.60 | GSK3B (0.34) | GSK3BTNKS2 | |
| SCHEMBL279883 | 0.60 | TSHR (0.44) | GSK3BTNKS2 | |
| SCHEMBL28362032 | 0.60 | GSK3B (0.35) | GSK3BTNKS2 | |
| SCHEMBL29550020 | 0.60 | GSK3B (0.35) | GSK3BTNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060163-B1 | NEW PIPERAZINYL-SUBSTITUTED PYRIDYLALKANE, ALKENE AND ALKINE CARBOXAMIDES | KLINGE CO CHEM PHARM FAB (DE) | 2005-10-12 | — | — | EP | claimed |
| EP-2958565-A1 | TRICYCLIC HETEROCYCLES AS ANTICANCER AGENTS | Icahn School of Medicine at Mount Sinai (US) | 2015-12-30 | — | — | EP | disclosed |
| WO-2014130534-A1 | TRICYCLIC HETEROCYCLES AS ANTICANCER AGENTS | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2014-08-28 | — | — | WO | disclosed |
| EP-1060163-B1 | NEW PIPERAZINYL-SUBSTITUTED PYRIDYLALKANE, ALKENE AND ALKINE CARBOXAMIDES | KLINGE CO CHEM PHARM FAB (DE) | 2005-10-12 | — | — | EP | disclosed |
| US-6903118-B1 | Piperazinyl-substituted pyridylalkane, alkene and alkine carboxamides | KLINGE PHARMA GMBH (DE) | 2005-06-07 | — | — | US | disclosed |