SCHEMBL460544

SCHEMBL460544

C1=CC2=CCc3ccccc3NC2C=C1

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6163801 0.77 GSK3B (0.31)
SCHEMBL2643485 0.71 GAA (0.33) GAAMAPT
SCHEMBL4232316 0.71 GAA (0.36) GAAMAPT
SCHEMBL15973038 0.68
SCHEMBL5904469 0.68 TNKS2 (0.36) GAA
SCHEMBL12096478 0.67
SCHEMBL869745 0.67
SCHEMBL7729429 0.67 AR (0.36) GAAMAPT
SCHEMBL20067380 0.64 BRD4 (0.31)
SCHEMBL7538817 0.64 ACHE (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024025260-A1 FLUORESCENT PROBE COMPOUND AND COMPOSITE COMPRISING SAME 한국생명공학연구원 2024-02-01 WO disclosed
WO-2022235077-A1 NOVEL SIDEROPHORE COMPOUND AND METAL NANOPARTICLE COMPLEX USING SAME 한국생명공학연구원 2022-11-10 WO disclosed
WO-2022211314-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, MANUFACTURING METHOD THEREFOR, AND COMPOSITION FOR ORGANIC LAYER 엘티소재주식회사 2022-10-06 WO disclosed
WO-2022186645-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, MANUFACTURING METHOD THEREFOR, AND COMPOSITION FOR ORGANIC LAYER 엘티소재주식회사 2022-09-09 WO disclosed
US-11302873-B2 Organic light-emitting device LT MATERIALS CO, LTD. (KR) 2022-04-12 US disclosed
EP-0751129-B3 Substituted dihydrodibenzo(b,f)azepines, method for their preparation, their use in the treatment of some central nervous system disorders, and pharmaceutical compositions containing them BIAL PORTELA & CA SA (PT) 2020-05-13 EP disclosed
EP-3350189-A1 METAL COMPLEXES UEA Enterprises Limited (GB) 2018-07-25 EP disclosed
WO-2017046572-A1 METAL COMPLEXES UNIVERSITY OF EAST ANGLIA (GB) 2017-03-23 WO disclosed
US-20120022047-A1 PROCESS FOR THE PURIFICATION OF ESLICARBAZEPINE ACETATE GLENMARK GENERICS LTD (IN) 2012-01-26 US disclosed
US-7863443-B2 Phosphoramidite ligand and production method of allylic amine using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-04 US disclosed
US-20060142566-A1 Enantioselective process for the preparation of both enantiomers of 10,11-dihydro-10-hydroxy-5h-dibenz[b,f]azepine-5-carboxamide and new crystal forms thereof NOVARTIS AG (CH) 2006-06-29 US disclosed
EP-1551808-A1 ENANTIOSELECTIVE PROCESS FOR THE PREPARATION OF BOTH ENANTIOMERS OF 10,11-DIHYDRO-10-HYDROXY-5H-DIBENZ b,f AZEPINE-5-CARBOXAMIDE AND NEW CRYSTAL FORMS THEREOF Novartis AG (CH) 2005-07-13 EP disclosed
EP-1551808-A1 ENANTIOSELECTIVE PROCESS FOR THE PREPARATION OF BOTH ENANTIOMERS OF 10,11-DIHYDRO-10-HYDROXY-5H-DIBENZ b,f AZEPINE-5-CARBOXAMIDE AND NEW CRYSTAL FORMS THEREOF Novartis AG (CH) 2005-07-13 EP disclosed
EP-1414806-A1 NOVEL VINYL N-(2-BENZOYLPHENYL)-L-TYROSINE DERIVATIVES AND THEIR USE AS ANTIDIABETICS ETC NOVO NORDISK A/S (DK) 2004-05-06 EP disclosed
WO-2004031155-A1 ENANTIOSELECTIVE PROCESS FOR THE PREPARATION OF BOTH ENANTIOMERS OF 10,11-DIHYDRO-10-HYDROXY-5H-DIBENZ [b,f]AZEPINE-5-CARBOXAMIDE AND NEW CRYSTAL FORMS THEREOF NOVARTIS AG (CH) 2004-04-15 WO disclosed
WO-2004031155-A1 ENANTIOSELECTIVE PROCESS FOR THE PREPARATION OF BOTH ENANTIOMERS OF 10,11-DIHYDRO-10-HYDROXY-5H-DIBENZ [b,f]AZEPINE-5-CARBOXAMIDE AND NEW CRYSTAL FORMS THEREOF NOVARTIS AG (CH) 2004-04-15 WO disclosed
WO-2003011834-A1 NOVEL VINYL N-(2-BENZOYLPHENYL)-L-TYROSINE DERIVATIVES AND THEIR USE AS ANTIDIABETICS ETC NOVO NORDISK A/S (DK) 2003-02-13 WO disclosed
WO-2001015656-A9 TRICYCLIC COMPOUNDS AND THEIR USES AS ANTIARRHYTHMIC ANTIFIBRILLATORY AND DEFIBRILLATORY AGENTS TECHNION RES & DEV FOUNDATION (IL) 2002-04-18 WO disclosed
WO-2001015656-A2 TRICYCLIC COMPOUNDS AND THEIR USES AS ANTIARRHYTHMIC ANTIFIBRILLATORY AND DEFIBRILLATORY AGENTS TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) 2001-03-08 WO disclosed
EP-0751129-B1 Substituted dihydrodibenzo(b,f)azepines, method for their preparation, their use in the treatment of some central nervous system disorders, and pharmaceutical compositions containing them PORTELA & CA SA (PT) 1998-11-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120022047-A1 PROCESS FOR THE PURIFICATION OF ESLICARBAZEPINE ACETATE CACNA1A, GABRE, CACNA1D GAA 525/4885MAPT 1581/4885
US-20060142566-A1 Enantioselective process for the preparation of both enantiomers of 10,11-dihydro-10-hydroxy-5h-dibenz[b,f]azepine-5-carboxamide and new crystal forms thereof HRH4, HRH1, HRH3 GAA 3259/4885MAPT 3488/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.