Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QDPR | P09417 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 8/20 | 0.41 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 4/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL788535 | 0.82 | QDPR (0.45) | QDPRHTR2CSLC18A3SIGMAR1TLR9 | |
| Hydrochloric Acid SCHEMBL5720133 | 0.71 | HPGD (0.40) | QDPRSLC18A3TLR9TLR8TLR7 | |
| SCHEMBL2334055 | 0.69 | EPHX2 (0.41) | QDPRMAPKAPK2EPHX2 | |
| SCHEMBL23442736 | 0.67 | QDPR (0.45) | QDPRHTR2CSLC18A3SIGMAR1TLR9 | |
| SCHEMBL6978487 | 0.67 | ESR2 (0.44) | DDB1CRBNEPHX2 | |
| SCHEMBL3827824 | 0.66 | EPHX2 (0.38) | EPHX2 | |
| SCHEMBL24067500 | 0.65 | SLC18A3 (0.64) | QDPRHTR2CSLC18A3SIGMAR1HRH4 | |
| SCHEMBL5586163 | 0.65 | QDPR (0.50) | QDPRHTR2CSLC18A3SIGMAR1MAPKAPK2 | |
| SCHEMBL3812218 | 0.65 | EPHX2 (0.75) | QDPRMAPKAPK2EPHX2 | |
| Hydrochloric Acid SCHEMBL31110442 | 0.64 | EPHX2 (0.73) | QDPRHTR2CMAPKAPK2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451173-A4 | PIPERIDINES | ICAGEN INC (US) | 2005-10-26 | — | — | EP | disclosed |
| EP-1451173-A2 | PIPERIDINES | Icagen, Inc. (US) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003037890-A2 | PIPERIDINES | ICAGEN, INC. (US) | 2003-05-08 | — | — | WO | disclosed |