Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 3/20 | 0.48 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.48 |
| ▸ | ITGAL | P20701 | 3/20 | 0.48 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | UGCG | Q16739 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6164458 | 1.00 | ITGB2 (0.48) | ITGB2ICAM1ITGALERAP2ACE | |
| Hydrochloric Acid SCHEMBL6161493 | 0.90 | ITGB2 (0.48) | ITGB2ICAM1ITGALERAP2ACE | |
| Hydrochloric Acid SCHEMBL6161499 | 0.90 | ITGB2 (0.48) | ITGB2ICAM1ITGALERAP2ACE | |
| SCHEMBL6163815 | 0.85 | MEN1 (0.47) | ITGB2ICAM1ITGALACEF10 | |
| SCHEMBL6163811 | 0.85 | MEN1 (0.47) | ITGB2ICAM1ITGALACEF10 | |
| SCHEMBL6161589 | 0.84 | MEN1 (0.45) | ITGB2ICAM1ITGALERAP2ACE | |
| SCHEMBL6161580 | 0.84 | MEN1 (0.45) | ITGB2ICAM1ITGALERAP2ACE | |
| SCHEMBL6162200 | 0.83 | MEN1 (0.45) | ITGB2ICAM1ITGALACETACR1 | |
| SCHEMBL6162193 | 0.83 | MEN1 (0.45) | ITGB2ICAM1ITGALACETACR1 | |
| Hydrochloric Acid SCHEMBL6160507 | 0.83 | GHSR (0.49) | ITGB2ICAM1ITGALERAP2ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | disclosed |