Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 16/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2351986 | 0.85 | TSHR (0.47) | PTGDR2PTPN1 | |
| SCHEMBL5366352 | 0.82 | PTGDR2 (0.50) | PTGDR2TDP1 | |
| SCHEMBL12082905 | 0.81 | RXRA (0.48) | PTGDR2 | |
| SCHEMBL6165389 | 0.80 | TDP1 (0.64) | PTGDR2PTPN1TDP1 | |
| SCHEMBL5763861 | 0.78 | S1PR3 (0.49) | PTGDR2TDP1 | |
| SCHEMBL4004421 | 0.78 | APEX1 (0.60) | PTGDR2PTPN1 | |
| SCHEMBL3240203 | 0.78 | PKM (0.59) | PTGDR2PTPN1TDP1 | |
| SCHEMBL4808533 | 0.77 | PTGDR2 (0.51) | PTGDR2TDP1 | |
| SCHEMBL23321157 | 0.77 | PTGDR2 (0.73) | PTGDR2TDP1 | |
| SCHEMBL17897051 | 0.77 | PTGDR2 (0.56) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392674-B1 | FURAN AND THIOPHENE DERIVATIVES THAT ACTIVATE HUMAN PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | SMITHKLINE BEECHAM CORP (US) | 2005-08-10 | — | — | EP | disclosed |
| EP-1392674-A1 | FURAN AND THIOPHENE DERIVATIVES THAT ACTIVATE HUMAN PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | GLAXO GROUP LIMITED (GB) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002092590-A1 | FURAN AND THIOPHENE DERIVATIVES THAT ACTIVATE HUMAN PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | GLAXO GROUP LIMITED (GB) | 2002-11-21 | — | — | WO | disclosed |