Phenol

Phenol

SCHEMBL616489

CCC(C)(C)C(C)(C)c1ccc(O)cc1.Oc1ccccc1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 14/20 0.53
ESR2 Q92731 13/20 0.53
CYP3A4 P08684 3/20 0.53
ALDH1A1 P00352 2/20 0.53
LMNA P02545 1/20 0.45
TYR P14679 1/20 0.45
AR P10275 1/20 0.45
HPGD P15428 1/20 0.45
TSHR P16473 1/20 0.45
SLC6A2 P23975 1/20 0.45
SLC6A4 P31645 1/20 0.45
HTR6 P50406 1/20 0.45
ESRRG P62508 1/20 0.45
SLC6A3 Q01959 1/20 0.45
HSD17B10 Q99714 1/20 0.45
SHBG P04278 1/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
GLA P06280 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26168 0.92 ESR1 (0.58) ESR1ESR2CYP3A4ALDH1A1LMNA
SCHEMBL11681932 0.88 ESR1 (0.54) ESR1ESR2CYP3A4ALDH1A1LMNA
SCHEMBL1287614 0.83 TAAR1 (0.44) ESR1ESR2CYP3A4ALDH1A1LMNA
Phenol SCHEMBL27712303 0.80 ESR1 (0.57) ESR1ESR2CYP3A4ALDH1A1LMNA
Phenol SCHEMBL8467840 0.80 ESR1 (0.57) ESR1ESR2CYP3A4ALDH1A1LMNA
SCHEMBL14597247 0.79 ESR1 (0.74) ESR1ESR2CYP3A4ALDH1A1LMNA
SCHEMBL31441290 0.77 ESR1 (0.41) ESR1ESR2CYP3A4ALDH1A1LMNA
SCHEMBL1767723 0.77 ESR1 (0.41) ESR1ESR2CYP3A4ALDH1A1LMNA
SCHEMBL29291135 0.77 ALDH1A1 (0.49) ALDH1A1LMNAHPGDTDP1
SCHEMBL23905030 0.76 ESR1 (0.63) ESR1ESR2CYP3A4ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8426531-B2 Method for monitoring monomer concentration in interfacial polycarbonate manufacturing process STYRON EUROPE GMBH (CH) 2013-04-23 US disclosed
US-20120041158-A1 Method for Monitoring Monomer Concentration In Interfacial Polycarbonate Manufacturing Process TRINSEO EUROPE GMBH (CH) 2012-02-16 US disclosed
US-20110288243-A1 Carbonate Block Copolymers JUEPTNER GUENTER A (DE) 2011-11-24 US disclosed
US-20110224372-A1 PROCESS FOR PREPARING LINEAR POLYCARBONATE WITH IMPROVED IMPACT PROPERTIES TRINSEO EUROPE GMBH (CH) 2011-09-15 US disclosed
US-20110224389-A1 METHOD FOR RECYCLING AMINE CATALYST IN INTERFACIAL POLYCARBONATE MANUFACTURING PROCESS STYRON EUROPE GMBH (CH) 2011-09-15 US disclosed