Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90B1 | P14625 | 3/20 | 0.32 |
| ▸ | TRAP1 | Q12931 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6165076 | 0.92 | HSP90B1 (0.32) | HSP90B1TRAP1HSP90AA1HSP90AB1MAOB | |
| SCHEMBL6967111 | 0.90 | HSP90B1 (0.31) | HSP90B1TRAP1HSP90AA1HSP90AB1 | |
| SCHEMBL8345609 | 0.85 | HDAC6 (0.39) | — | |
| SCHEMBL6162100 | 0.84 | DGKA (0.39) | — | |
| SCHEMBL6964428 | 0.84 | TLR8 (0.33) | HSP90B1TRAP1HSP90AA1HSP90AB1 | |
| SCHEMBL6960253 | 0.83 | PTGDR2 (0.32) | HSP90B1TRAP1HSP90AA1HSP90AB1 | |
| SCHEMBL6963069 | 0.83 | HSP90B1 (0.34) | HSP90B1TRAP1HSP90AA1HSP90AB1 | |
| SCHEMBL6970240 | 0.83 | L3MBTL1 (0.36) | HSP90B1 | |
| SCHEMBL6159225 | 0.82 | — | — | |
| SCHEMBL6973990 | 0.82 | MEN1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0893442-B1 | LYMPH-ABSORBABLE IMIDAZOLE DERIVATIVES | SHIONOGI & CO (JP) | 2005-01-12 | — | — | EP | disclosed |
| US-6054591-A | LYMPHOTROPIC ANTI-AIDS AGENT | SHIONOGI & CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| EP-0893442-A1 | LYMPH-ABSORBABLE IMIDAZOLE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 1999-01-27 | — | — | EP | disclosed |