Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4288379 | 0.89 | EGLN3 (0.69) | TBXAS1EGLN3 | |
| Hydrochloric Acid SCHEMBL3642733 | 0.87 | EGLN3 (0.67) | TBXAS1EGLN3 | |
| SCHEMBL2436663 | 0.83 | TBXAS1 (0.86) | TBXAS1EGLN3 | |
| SCHEMBL4395522 | 0.83 | TBXAS1 (0.64) | TBXAS1EGLN3 | |
| SCHEMBL24040195 | 0.82 | TBXAS1 (0.58) | TBXAS1EGLN3 | |
| Hydrochloric Acid SCHEMBL8891869 | 0.81 | TBXAS1 (0.87) | TBXAS1EGLN3 | |
| SCHEMBL26118476 | 0.81 | TBXAS1 (0.62) | TBXAS1EGLN3 | |
| SCHEMBL23844568 | 0.81 | TBXAS1 (0.57) | TBXAS1EGLN3 | |
| SCHEMBL5612857 | 0.81 | TBXAS1 (0.55) | TBXAS1EGLN3 | |
| SCHEMBL10785082 | 0.81 | TBXAS1 (0.59) | TBXAS1EGLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210292300-A1 | DIMETHOXYPHENYL SUBSTITUTED INDOLE COMPOUNDS AS TLR7, TLR8 OR TLR9 INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2021-09-23 | — | — | US | disclosed |
| EP-3490983-B1 | DIMETHOXYPHENYL SUBSTITUTED INDOLE COMPOUNDS AS TLR7, TLR8 OR TLR9 INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2021-02-17 | — | — | EP | disclosed |
| WO-2018026620-A1 | DIMETHOXYPHENYL SUBSTITUTED INDOLE COMPOUNDS AS TLR7, TLR8 OR TLR9 INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-02-08 | — | — | WO | disclosed |
| EP-1250335-B1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF IMIDAZOPYRIDINES | ALTANA PHARMA AG (DE) | 2005-07-27 | — | — | EP | disclosed |
| EP-0094080-B1 | PYRIDO(2,1-B)QUINAZOLINE DERIVATIVES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1987-09-09 | — | — | EP | disclosed |
| US-4551460-A | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1985-11-05 | — | — | US | disclosed |
| EP-0094080-A2 | Pyrido(2,1-b)quinazoline derivatives | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1983-11-16 | — | — | EP | disclosed |
| US-4059705-A | FUNGICIDE, BACTERICIDE, ANTIPROTOZOA | SYNTEX (U.S.A.) INC. (US) | 1977-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210292300-A1 | DIMETHOXYPHENYL SUBSTITUTED INDOLE COMPOUNDS AS TLR7, TLR8 OR TLR9 INHIBITORS | TLR9, TLR7, TLR8 | TBXAS1 1361/4885EGLN3 2500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.