Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 17/20 | 0.57 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.54 |
| ▸ | QPCT | Q16769 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8640926 | 0.90 | EGLN3 (0.62) | TBXAS1EGLN3 | |
| SCHEMBL6165743 | 0.81 | TBXAS1 (0.62) | TBXAS1EGLN3 | |
| SCHEMBL12391736 | 0.80 | ALDH1A1 (0.62) | TBXAS1EGLN3 | |
| SCHEMBL4395522 | 0.79 | TBXAS1 (0.64) | TBXAS1EGLN3 | |
| SCHEMBL2436663 | 0.79 | TBXAS1 (0.86) | TBXAS1EGLN3 | |
| SCHEMBL1828857 | 0.79 | TBXAS1 (0.64) | TBXAS1EGLN3 | |
| SCHEMBL47372 | 0.78 | EGLN3 (0.61) | TBXAS1EGLN3 | |
| SCHEMBL24040195 | 0.78 | TBXAS1 (0.58) | TBXAS1EGLN3 | |
| Hydrochloric Acid SCHEMBL8891869 | 0.77 | TBXAS1 (0.87) | TBXAS1EGLN3 | |
| SCHEMBL26118476 | 0.77 | TBXAS1 (0.62) | TBXAS1EGLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210292300-A1 | DIMETHOXYPHENYL SUBSTITUTED INDOLE COMPOUNDS AS TLR7, TLR8 OR TLR9 INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2021-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210292300-A1 | DIMETHOXYPHENYL SUBSTITUTED INDOLE COMPOUNDS AS TLR7, TLR8 OR TLR9 INHIBITORS | TLR9, TLR7, TLR8 | TBXAS1 1361/4885EGLN3 2500/4885QPCT 3661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.