Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.40 |
| ▸ | MTOR | P42345 | 2/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.39 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6167175 | 1.00 | RAB9A (0.50) | RAB9AAURKATRPV1PIK3CAMTOR | |
| SCHEMBL6163701 | 1.00 | RAB9A (0.50) | RAB9AAURKATRPV1PIK3CAMTOR | |
| SCHEMBL6164570 | 0.91 | RAB9A (0.48) | RAB9AAURKATRPV1HCRTR1HCRTR2 | |
| SCHEMBL6162269 | 0.91 | RAB9A (0.48) | RAB9AAURKATRPV1HCRTR1HCRTR2 | |
| SCHEMBL6162329 | 0.91 | RAB9A (0.48) | RAB9AAURKATRPV1HCRTR1HCRTR2 | |
| SCHEMBL6165986 | 0.90 | TRPV1 (0.51) | RAB9AAURKATRPV1HCRTR1HCRTR2 | |
| SCHEMBL6163471 | 0.88 | TRPV1 (0.51) | RAB9ATRPV1 | |
| SCHEMBL6162108 | 0.88 | TRPV1 (0.51) | RAB9ATRPV1 | |
| SCHEMBL6163748 | 0.88 | TRPV1 (0.51) | RAB9ATRPV1 | |
| SCHEMBL6167551 | 0.87 | RAB9A (0.49) | RAB9ATRPV1HCRTR1HCRTR2PLAUR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1337523-B1 | 2,4-SUBSTITUTED PYRIDINE DERIVATIVES | NEUROGEN CORP (US) | 2005-10-19 | — | — | EP | claimed |