Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.58 |
| ▸ | TBXAS1 | P24557 | 14/20 | 0.51 |
| ▸ | CDK1 | P06493 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10955136 | 0.88 | TBXAS1 (0.51) | ERN1TBXAS1 | |
| SCHEMBL11457521 | 0.82 | IDH1 (0.63) | ERN1CDK1 | |
| SCHEMBL283097 | 0.82 | CDK1 (0.69) | ERN1CDK1 | |
| SCHEMBL10702687 | 0.81 | IDH1 (0.61) | TBXAS1 | |
| SCHEMBL10955316 | 0.80 | TBXAS1 (0.43) | TBXAS1 | |
| SCHEMBL10955314 | 0.80 | TBXAS1 (0.43) | TBXAS1 | |
| SCHEMBL10958433 | 0.79 | TBXAS1 (0.47) | ERN1TBXAS1 | |
| SCHEMBL10949427 | 0.79 | TBXAS1 (0.46) | ERN1TBXAS1 | |
| SCHEMBL21096809 | 0.77 | CDK1 (0.54) | ERN1CDK1 | |
| SCHEMBL10950406 | 0.77 | ESR1 (0.65) | TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1044974-B1 | N-HYDROXYUREA DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | NIKKEN CHEMICALS CO LTD (JP) | 2005-07-20 | — | — | EP | disclosed |
| US-6291482-B1 | THROMBOXANE SYNTHASE INHIBITORY ANTI-INFLAMMATORY DRUG COMPRISING N-HYDROXY-N-(6-(3-PYRIDYMETHYL)-2H-1-BENZOPYRAN-3-YLMETHYL)URE A; ANTIALLERGIC, ANTIASTHMATIC | NIKKEN CHEMICALS CO., LTD (JP) | 2001-09-18 | — | — | US | disclosed |
| EP-1044974-A1 | N-HYDROXYUREA DERIVATIVE AND MEDICINE CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 2000-10-18 | — | — | EP | disclosed |
| US-4495357-A | THROMBOXANE A2 SYNTHETASE INHIBITORS | THE UPJOHN COMPANY (US) | 1985-01-22 | — | — | US | disclosed |
| EP-0069521-A2 | Pyridinyl and imidazolyl derivatives of benzofurans and benzothiophenes | THE UPJOHN COMPANY (US) | 1983-01-12 | — | — | EP | disclosed |