Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6167587 | 0.85 | KDM4C (0.33) | KDM4CNPC1RAB9AMEN1KMT2A | |
| SCHEMBL30407540 | 0.82 | KDM4C (0.37) | KDM4CNPC1RAB9AMEN1KMT2A | |
| SCHEMBL21738201 | 0.82 | MEN1 (0.42) | KDM4CNPC1RAB9AMEN1KMT2A | |
| SCHEMBL12435177 | 0.80 | MEN1 (0.39) | KDM4CNPC1RAB9AMEN1KMT2A | |
| SCHEMBL6535753 | 0.78 | KDM4C (0.34) | KDM4CNPC1RAB9AMEN1KMT2A | |
| SCHEMBL9195356 | 0.78 | MEN1 (0.40) | KDM4CNPC1RAB9AMEN1KMT2A | |
| SCHEMBL10560537 | 0.78 | MEN1 (0.41) | KDM4CNPC1RAB9AMEN1KMT2A | |
| SCHEMBL6534702 | 0.77 | KDM4C (0.34) | KDM4CNPC1RAB9AMEN1KMT2A | |
| SCHEMBL23014968 | 0.77 | MEN1 (0.43) | KDM4CNPC1RAB9AMEN1KMT2A | |
| SCHEMBL23014844 | 0.77 | MEN1 (0.43) | KDM4CNPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11161827-B2 | Catalytic systems for stereoselective synthesis of chiral amines by enantiodivergent radical C—H amination | THE TRUSTEES OF BOSTON COLLEGE (MA) | 2021-11-02 | — | — | US | disclosed |
| US-11161827-B2 | Catalytic systems for stereoselective synthesis of chiral amines by enantiodivergent radical C—H amination | THE TRUSTEES OF BOSTON COLLEGE (MA) | 2021-11-02 | — | — | US | disclosed |
| US-20200317627-A1 | CATALYTIC SYSTEMS FOR STEREOSELECTIVE SYNTHESIS OF CHIRAL AMINES BY ENANTIODIVERGENT RADICAL C-H AMINATION | TRUSTEES OF BOSTON COLLEGE (US) | 2020-10-08 | — | — | US | disclosed |
| US-20200317627-A1 | CATALYTIC SYSTEMS FOR STEREOSELECTIVE SYNTHESIS OF CHIRAL AMINES BY ENANTIODIVERGENT RADICAL C-H AMINATION | TRUSTEES OF BOSTON COLLEGE (US) | 2020-10-08 | — | — | US | disclosed |
| EP-1379511-B1 | DIHYDRO-BENZO (b) (1, 4) DIAZEPIN-2-ONE DERIVATIVES AS MGLUR2 ANTAGONISTS II | HOFFMANN LA ROCHE (CH) | 2005-07-20 | — | — | EP | disclosed |
| EP-1379511-A1 | DIHYDRO-BENZO (b) (1, 4) DIAZEPIN-2-ONE DERIVATIVES AS MGLUR2 ANTAGONISTS II | F. HOFFMANN-LA ROCHE AG (CH) | 2004-01-14 | — | — | EP | disclosed |
| US-6544985-B2 | For therapy of acute and/or chronic neurological disorders such as psychosis, schizophrenia, Alzheimer's disease, cognitive disorders and memory deficits | HOFFMAN-LA ROCHE INC. | 2003-04-08 | — | — | US | disclosed |
| US-20020193367-A1 | Dihydro-benzo [b] [1,4] diazepin-2-one derivatives | F. HOFFMAN-LA ROCHE AG A SWISS COMPANY (CH) | 2002-12-19 | — | — | US | disclosed |
| WO-2002083652-A1 | DIHYDRO-BENZO [b] [1, 4] DIAZEPIN-2-ONE DERIVATIVES AS MGLUR2 ANTAGONISTS II | F. HOFFMANN-LA ROCHE AG (CH) | 2002-10-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11161827-B2 | Catalytic systems for stereoselective synthesis of chiral amines by enantiodivergent radical C—H amination | STS, SRM, SCLY | KDM4C 596/4885NPC1 4671/4885RAB9A 3335/4885 |
| US-20200317627-A1 | CATALYTIC SYSTEMS FOR STEREOSELECTIVE SYNTHESIS OF CHIRAL AMINES BY ENANTIODIVERGENT RADICAL C-H AMINATION | STS, SCLY, SRM | KDM4C 673/4885NPC1 4643/4885RAB9A 3333/4885 |
| US-20020193367-A1 | Dihydro-benzo [b] [1,4] diazepin-2-one derivatives | CYP1B1, GRIN2B, BDKRB1 | KDM4C 1086/4885NPC1 947/4885RAB9A 1379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.