Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 7/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 3/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6350652 | 0.83 | HPGD (0.50) | HPGDDYRK1AMAPTKMT2AMEN1 | |
| SCHEMBL25449 | 0.73 | MAPK1 (0.57) | HPGDDYRK1AMAPTKMT2AMEN1 | |
| SCHEMBL27725624 | 0.73 | HPGD (0.43) | HPGDDYRK1AMAPTKMT2AMEN1 | |
| SCHEMBL16175225 | 0.73 | HPGD (0.39) | HPGDDYRK1AMAPTKMT2AMEN1 | |
| SCHEMBL8521461 | 0.72 | MAPK1 (0.35) | HPGDMAPTKDM4EMAPK1ALDH1A1 | |
| SCHEMBL2359207 | 0.72 | HPGD (0.43) | HPGDDYRK1AMAPTKMT2AMEN1 | |
| SCHEMBL16077518 | 0.71 | HPGD (0.54) | HPGDMAPTKMT2AMEN1KDM4E | |
| SCHEMBL20262820 | 0.70 | HPGD (0.43) | HPGDDYRK1AKMT2AMEN1LMNA | |
| SCHEMBL27706813 | 0.70 | HPGD (0.40) | HPGDDYRK1AMAPTKMT2AKDM4E | |
| SCHEMBL6722955 | 0.70 | HPGD (0.46) | HPGDMAPTKMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1503990-A1 | ACTIVE SUBSTANCES FOR THE TREATMENT, DIAGNOSIS AND PROPHYLAXIS OF DISEASES IN WHICH ABNORMAL PROTEIN STRUCTURES OCCUR | Transmit Gesellschaft für Technologietransfer mbH (DE) | 2005-02-09 | — | — | EP | disclosed |
| WO-2003095429-A1 | ACTIVE SUBSTANCES FOR THE TREATMENT, DIAGNOSIS AND PROPHYLAXIS OF DISEASES IN WHICH ABNORMAL PROTEIN STRUCTURES OCCUR | TransMIT Gesellschaft für Technologietransfer mbH (DE) | 2003-11-20 | — | — | WO | disclosed |