Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 2/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
| ▸ | CCKBR | P32239 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6166340 | 1.00 | ITGB1 (0.37) | ITGB1ITGA4CHEK1NTRK1NTRK2 | |
| SCHEMBL6163576 | 0.92 | ITGA4 (0.40) | ITGB1ITGA4CHEK1MEN1MAPT | |
| SCHEMBL6163582 | 0.92 | ITGA4 (0.40) | ITGB1ITGA4CHEK1MEN1MAPT | |
| SCHEMBL6166269 | 0.92 | ITGB1 (0.40) | ITGB1ITGA4CHEK1NTRK1NTRK2 | |
| SCHEMBL6166262 | 0.92 | ITGB1 (0.40) | ITGB1ITGA4CHEK1NTRK1NTRK2 | |
| SCHEMBL6166201 | 0.90 | ITGB1 (0.42) | ITGB1ITGA4CHEK1NTRK1NTRK2 | |
| SCHEMBL4671581 | 0.85 | ITGA4 (0.46) | ITGB1ITGA4CHEK1MEN1MAPT | |
| SCHEMBL4671585 | 0.85 | ITGA4 (0.46) | ITGB1ITGA4CHEK1MEN1MAPT | |
| SCHEMBL6162555 | 0.85 | ITGA4 (0.46) | ITGB1ITGA4CHEK1MEN1MAPT | |
| SCHEMBL6162542 | 0.85 | ITGA4 (0.46) | ITGB1ITGA4CHEK1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373249-B1 | IMIDAZOLIDINE DERIVATIVES, THEIR PREPARATION, AND THEIR USE AS ANTIINFLAMATORY AGENT | AVENTIS PHARMA GMBH (DE) | 2005-04-20 | — | — | EP | disclosed |
| EP-1373249-A1 | IMIDAZOLIDINE DERIVATIVES, THEIR PREPARATION, AND THEIR USE AS ANTINFLAMATORY AGENT | Aventis Pharma Deutschland GmbH (DE) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002072573-A1 | IMIDAZOLIDINE DERIVATIVES, THEIR PREPARATION, AND THEIR USE AS ANTINFLAMATORY AGENT. | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-09-19 | — | — | WO | disclosed |