SCHEMBL616692

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL615667	0.89	MEN1 (0.51)	MEN1KMT2AMAPTMAPK1ATM
	SCHEMBL618924	0.89	MEN1 (0.63)	MEN1KMT2AMAPTMAPK1ATM
	SCHEMBL616210	0.88	PTGS2 (0.52)	MEN1KMT2AMAPTMAPK1ATM
	SCHEMBL617982	0.88	MAPT (0.59)	MEN1KMT2AMAPTMAPK1ATM
	SCHEMBL617566	0.88	MAPT (0.51)	MEN1KMT2AMAPTMAPK1ATM
	SCHEMBL616208	0.87	MEN1 (0.47)	MEN1KMT2AMAPTMAPK1ATM
	SCHEMBL14537090	0.86	MEN1 (0.48)	MEN1KMT2AMAPTMAPK1ATM
	SCHEMBL619170	0.85	MEN1 (0.47)	MEN1KMT2AMAPTMAPK1ATM
	SCHEMBL10188809	0.84	PTGS2 (0.37)	MEN1KMT2APTGS2GAAHSP90AA1
	SCHEMBL10242314	0.83	MEN1 (0.47)	MEN1KMT2AMAPTMAPK1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.