Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27878889 | 0.90 | ALDH1A1 (0.50) | ALDH1A1POLBHTTCYP1A2GAA | |
| SCHEMBL6169286 | 0.90 | ALDH1A1 (0.50) | ALDH1A1POLBHTTCYP1A2GAA | |
| SCHEMBL6168133 | 0.82 | ALDH1A1 (0.41) | ALDH1A1POLBHTTCYP1A2GAA | |
| SCHEMBL1576768 | 0.81 | ALDH1A1 (0.53) | ALDH1A1POLBHTTCYP1A2GAA | |
| SCHEMBL6169282 | 0.80 | ALDH1A1 (0.52) | ALDH1A1POLBHTTCYP1A2GAA | |
| SCHEMBL21245001 | 0.79 | ALDH1A1 (0.64) | ALDH1A1POLBHTTCYP1A2GAA | |
| SCHEMBL26104511 | 0.79 | ALDH1A1 (0.50) | ALDH1A1POLBHTTCYP1A2GAA | |
| SCHEMBL26103485 | 0.76 | ALDH1A1 (0.48) | ALDH1A1POLBHTTCYP1A2GAA | |
| SCHEMBL26102819 | 0.75 | ALDH1A1 (0.45) | ALDH1A1POLBHTTCYP1A2GAA | |
| SCHEMBL13387618 | 0.74 | MAPT (0.47) | ALDH1A1POLBHTTCYP1A2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1503990-A1 | ACTIVE SUBSTANCES FOR THE TREATMENT, DIAGNOSIS AND PROPHYLAXIS OF DISEASES IN WHICH ABNORMAL PROTEIN STRUCTURES OCCUR | Transmit Gesellschaft für Technologietransfer mbH (DE) | 2005-02-09 | — | — | EP | disclosed |
| WO-2003095429-A1 | ACTIVE SUBSTANCES FOR THE TREATMENT, DIAGNOSIS AND PROPHYLAXIS OF DISEASES IN WHICH ABNORMAL PROTEIN STRUCTURES OCCUR | TransMIT Gesellschaft für Technologietransfer mbH (DE) | 2003-11-20 | — | — | WO | disclosed |