Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | CLK2 | P49760 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29391687 | 0.85 | ADRB2 (0.61) | ADRB2GSK3BKCNH2KDM4EALDH1A1 | |
| SCHEMBL1989474 | 0.85 | ADRB2 (0.61) | ADRB2GSK3BKCNH2KDM4EALDH1A1 | |
| SCHEMBL9149987 | 0.83 | MAPT (0.35) | KDM4EALDH1A1HPGDPOLBTDP1 | |
| SCHEMBL6481381 | 0.83 | MAPT (0.35) | KDM4EALDH1A1HPGDPOLBTDP1 | |
| SCHEMBL6221696 | 0.83 | MAPT (0.35) | KDM4EALDH1A1HPGDPOLBTDP1 | |
| SCHEMBL1342473 | 0.81 | ADRB2 (0.56) | ADRB2GSK3BKCNH2KDM4EALDH1A1 | |
| SCHEMBL12586937 | 0.81 | ADRB2 (0.56) | ADRB2GSK3BKCNH2KDM4EALDH1A1 | |
| SCHEMBL6177904 | 0.80 | ADRB2 (0.45) | ADRB2GSK3BKCNH2ALDH1A1POLB | |
| SCHEMBL1344190 | 0.79 | MAPK1 (0.36) | KDM4EALDH1A1TDP1LMNAMEN1 | |
| SCHEMBL12427257 | 0.79 | MAPK1 (0.34) | KDM4EALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532137-A2 | ANTIMICROBIAL AZA-BICYCLIC DERIVATES, THEIR COMPOSITIONS AND USES | THE PROCTER & GAMBLE COMPANY (US) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004014893-A2 | ANTIMICROBIAL AZA-BICYCLIC DERIVATES, THEIR COMPOSITIONS AND USES | THE PROCTER & GAMBLE COMPANY (US) | 2004-02-19 | — | — | WO | disclosed |