Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TOP2A | P11388 | 4/20 | 0.33 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4476600 | 0.85 | ADRB2 (0.55) | ADRB2ALDH1A1POLBCHRM2CHRM1 | |
| SCHEMBL6475919 | 0.83 | GPR35 (0.37) | ALDH1A1POLBKMT2ALMNA | |
| SCHEMBL4464475 | 0.83 | GPR35 (0.37) | ALDH1A1POLBKMT2ALMNA | |
| SCHEMBL6166978 | 0.80 | ADRB2 (0.49) | ADRB2ALDH1A1POLBOPRM1KMT2A | |
| SCHEMBL7575069 | 0.76 | ADRB2 (0.61) | ADRB2ALDH1A1POLBCHRM2CHRM1 | |
| SCHEMBL10472998 | 0.76 | ADRB2 (0.57) | ADRB2ALDH1A1POLBCHRM2CHRM1 | |
| SCHEMBL4564641 | 0.76 | ADRB2 (0.57) | ADRB2ALDH1A1POLBCHRM2CHRM1 | |
| SCHEMBL7584091 | 0.74 | ADRB2 (0.57) | ADRB2ALDH1A1POLBCHRM2CHRM1 | |
| SCHEMBL8437121 | 0.74 | POLB (0.39) | ALDH1A1POLBKMT2ALMNA | |
| SCHEMBL8436286 | 0.74 | MAPT (0.36) | ALDH1A1POLBKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532137-A2 | ANTIMICROBIAL AZA-BICYCLIC DERIVATES, THEIR COMPOSITIONS AND USES | THE PROCTER & GAMBLE COMPANY (US) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004014893-A2 | ANTIMICROBIAL AZA-BICYCLIC DERIVATES, THEIR COMPOSITIONS AND USES | THE PROCTER & GAMBLE COMPANY (US) | 2004-02-19 | — | — | WO | disclosed |