Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 5/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.39 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.39 |
| ▸ | BRS3 | P32247 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TYMS | P04818 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6165503 | 0.87 | SNCA (0.44) | SNCAHRH3FFAR1FFAR4MEP1B | |
| SCHEMBL6167457 | 0.86 | SNCA (0.37) | SNCA | |
| SCHEMBL6164368 | 0.85 | SNCA (0.41) | SNCAHRH3FFAR1FFAR4MEP1B | |
| SCHEMBL6161520 | 0.85 | SMN1; SMN2 (0.53) | SNCALMNA | |
| SCHEMBL6166657 | 0.83 | MAPT (0.44) | SNCAHRH3FFAR1FFAR4LMNA | |
| SCHEMBL6203639 | 0.82 | CACNA1F (0.43) | SNCAHRH3LMNA | |
| SCHEMBL6163170 | 0.82 | SMN1; SMN2 (0.52) | SNCALMNA | |
| SCHEMBL6162430 | 0.81 | SMN1; SMN2 (0.60) | SNCALMNA | |
| SCHEMBL6164246 | 0.81 | MAPT (0.46) | SNCALMNA | |
| SCHEMBL6165873 | 0.81 | MAPT (0.46) | SNCALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254136-A4 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG CHEM INVESTMENT LTD (KR) | 2005-06-01 | — | — | EP | disclosed |
| EP-1254136-A1 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG Chem Investment, Ltd. (KR) | 2002-11-06 | — | — | EP | disclosed |
| WO-2001055146-A1 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG CHEM INVESTMENT LTD. (KR) | 2001-08-02 | — | — | WO | disclosed |