Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 14/20 | 0.61 |
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.47 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6163962 | 0.91 | KCNN4 (0.55) | KCNN4KIF11KCNE1KCNQ1TSHR | |
| SCHEMBL7101543 | 0.91 | KCNN4 (0.55) | KCNN4KIF11KCNE1KCNQ1TSHR | |
| SCHEMBL6165966 | 0.85 | KCNN4 (0.59) | KCNN4KIF11KCNE1KCNQ1TSHR | |
| SCHEMBL812971 | 0.82 | KCNN4 (0.76) | KCNN4KCNE1KCNQ1TSHRMAPT | |
| Benzonitrile SCHEMBL15822038 | 0.76 | TSHR (0.70) | TSHRMAPTKMT2AALDH1A1LMNA | |
| Benzonitrile SCHEMBL7379370 | 0.76 | TSHR (0.70) | TSHRMAPTKMT2AALDH1A1LMNA | |
| Senicapoc SCHEMBL1443805 | 0.76 | KCNN4 (1.00) | KCNN4KIF11KCNE1KCNQ1MAPT | |
| SCHEMBL18782553 | 0.76 | KCNN4 (0.72) | KCNN4KIF11KCNE1KCNQ1TSHR | |
| SCHEMBL2337394 | 0.76 | KCNN4 (1.00) | KCNN4KIF11KCNE1KCNQ1MAPT | |
| SCHEMBL914557 | 0.75 | CYP3A4 (0.57) | KIF11TSHRMAPTPTPN5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254136-A4 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG CHEM INVESTMENT LTD (KR) | 2005-06-01 | — | — | EP | disclosed |
| US-20030065176-A1 | Factor xa inhibitors with aryl-amidines and derivatives, and prodrugs thereof | LG CHEM INVESTMENT LTD. (KR) | 2003-04-03 | — | — | US | disclosed |
| EP-1254136-A1 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG Chem Investment, Ltd. (KR) | 2002-11-06 | — | — | EP | disclosed |
| WO-2001055146-A1 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG CHEM INVESTMENT LTD. (KR) | 2001-08-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065176-A1 | Factor xa inhibitors with aryl-amidines and derivatives, and prodrugs thereof | F2, F12, TFPI | KCNN4 4024/4885KIF11 4602/4885KCNE1 3379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.