Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 12/20 | 0.55 |
| ▸ | KIF11 | P52732 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.41 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
| ▸ | VNN1 | O95497 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6163962 | 1.00 | KCNN4 (0.55) | KCNN4KIF11MEN1ALDH1A1MAPT | |
| SCHEMBL6165966 | 0.95 | KCNN4 (0.59) | KCNN4KIF11MAPTKMT2AKCNE1 | |
| SCHEMBL6167052 | 0.91 | KCNN4 (0.61) | KCNN4KIF11ALDH1A1MAPTKMT2A | |
| SCHEMBL1689259 | 0.78 | KIF11 (0.44) | KCNN4KIF11MEN1ALDH1A1MAPT | |
| SCHEMBL812971 | 0.75 | KCNN4 (0.76) | KCNN4MAPTKMT2AKCNE1KCNQ1 | |
| Benzonitrile SCHEMBL15822038 | 0.73 | TSHR (0.70) | MEN1ALDH1A1MAPTKMT2ATSHR | |
| Benzonitrile SCHEMBL7379370 | 0.73 | TSHR (0.70) | MEN1ALDH1A1MAPTKMT2ATSHR | |
| SCHEMBL13950934 | 0.71 | KCNN4 (1.00) | KCNN4KIF11MAPTKMT2AKCNE1 | |
| SCHEMBL22285654 | 0.70 | PTPN5 (0.46) | KIF11MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL14437487 | 0.70 | KCNN4 (1.00) | KCNN4MAPTKMT2AKCNE1KCNQ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030065176-A1 | Factor xa inhibitors with aryl-amidines and derivatives, and prodrugs thereof | LG CHEM INVESTMENT LTD. (KR) | 2003-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065176-A1 | Factor xa inhibitors with aryl-amidines and derivatives, and prodrugs thereof | F2, F12, TFPI | KCNN4 4024/4885KIF11 4602/4885MEN1 3229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.