Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 3/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1159787 | 0.70 | POLB (0.45) | KMT2AL3MBTL1POLBMEN1TSHR | |
| SCHEMBL7454892 | 0.67 | KMT2A (0.41) | KMT2AL3MBTL1POLBMEN1TSHR | |
| SCHEMBL4408725 | 0.67 | L3MBTL1 (0.50) | KMT2AL3MBTL1POLBMEN1TSHR | |
| SCHEMBL4596857 | 0.66 | KMT2A (0.44) | KMT2AL3MBTL1POLBMEN1TSHR | |
| SCHEMBL21169208 | 0.65 | POLB (0.43) | KMT2AL3MBTL1POLBMEN1TSHR | |
| SCHEMBL1513862 | 0.63 | POLB (0.42) | KMT2AL3MBTL1POLBMEN1TSHR | |
| SCHEMBL23894843 | 0.62 | KMT2A (0.41) | KMT2AMEN1TSHRLMNAMMP2 | |
| SCHEMBL31488478 | 0.62 | KMT2A (0.40) | KMT2APOLBMEN1TSHRAR | |
| SCHEMBL2135683 | 0.61 | POLB (0.36) | KMT2AL3MBTL1POLBMEN1TSHR | |
| SCHEMBL12329867 | 0.60 | L3MBTL1 (0.37) | KMT2AL3MBTL1POLBMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711758-B1 | Method of manufacturing a 3-substituted-3-oxo-2-halopropionic acid amide compound and method of manufacturing a 3-substituted-3-oxo-2-(5,5-dimethylhydantoin-3-yl) propionic acid amide compound | FUJI PHOTO FILM CO LTD (JP) | 2005-01-26 | — | — | EP | claimed |
| EP-1020450-B1 | 3-substituted-3-oxo-2-(5,5-dimethylhydantoin-3-yl) propionic acid amide compound and process for preparation thereof | FUJI PHOTO FILM CO LTD (JP) | 2004-02-11 | — | — | EP | disclosed |