SCHEMBL6167702

SCHEMBL6167702

CCOC(=O)CNC(=O)Cn1cc(C)c(=O)[nH]c1=O

nearest known ligand 0.51

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.51
LMNA P02545 2/20 0.46
TK1 P04183 5/20 0.45
HPGD P15428 2/20 0.45
KDM4E B2RXH2 1/20 0.45
USP2 O75604 1/20 0.45
ALDH1A1 P00352 1/20 0.45
HSD17B10 Q99714 1/20 0.45
RXFP1 Q9HBX9 3/20 0.43
POLB P06746 1/20 0.43
GAA P10253 1/20 0.43
MAPK1 P28482 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5962125 0.88 KMT2A (0.45) KMT2ALMNATK1HPGDMAPK1
SCHEMBL905269 0.85 LMNA (0.49) KMT2ALMNATK1HPGDMAPK1
SCHEMBL14255480 0.85 KMT2A (0.51) KMT2ALMNATK1HPGDMAPK1
SCHEMBL3516690 0.84 KMT2A (0.68) KMT2ALMNATK1HPGDMAPK1
SCHEMBL23328752 0.79 MAPK1 (0.50) KMT2ALMNATK1HPGDMAPK1
SCHEMBL23329069 0.78 TK1 (0.53) KMT2ALMNATK1GAA
SCHEMBL7643586 0.77 MAPK1 (0.51) KMT2ATK1HPGDMAPK1
SCHEMBL21695505 0.76 LMNA (0.74) KMT2ALMNATK1HPGDMAPK1
SCHEMBL23328426 0.75 MAPK1 (0.47) KMT2ALMNATK1HPGDMAPK1
SCHEMBL23328870 0.75 TYMP (0.48) KMT2ALMNATK1HPGDMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1470114-A4 PEPTIDE NUCLEIC ACID OLIGOMERS FROM 1-BENZENESULFONYL-3-AMINO ACID SIDE CHAIN-4-(2-NUCLEOBASE(ACETYL))-PIPERAZIN-2-ONES PANAGENE INC (KR) 2005-05-11 EP disclosed
EP-1470114-A1 PEPTIDE NUCLEIC ACID OLIGOMERS FROM 1-BENZENESULFONYL-3-AMINO ACID SIDE CHAIN-4-(2-NUCLEOBASE(ACETYL))-PIPERAZIN-2-ONES Panagene, Inc. (KR) 2004-10-27 EP disclosed
WO-2003062212-A1 PEPTIDE NUCLEIC ACID OLIGOMERS FROM 1-BENZENESULFONYL-3-AMINO ACID SIDE CHAIN-4-(2-NUCLEOBASE(ACETYL))-PIPERAZIN-2-ONES PANAGENE, INC. (US) 2003-07-31 WO disclosed