Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GALR2 | O43603 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | CCR6 | P51684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6807009 | 1.00 | KCNH2 (0.49) | KCNH2HCAR3KMT2AIDO1CNR2 | |
| SCHEMBL6922866 | 1.00 | KCNH2 (0.49) | KCNH2HCAR3KMT2AIDO1CNR2 | |
| SCHEMBL6167712 | 0.87 | KCNH2 (0.49) | KCNH2KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL6167720 | 0.87 | KCNH2 (0.49) | KCNH2KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL6167716 | 0.87 | KCNH2 (0.49) | KCNH2KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL6166252 | 0.86 | KCNH2 (0.49) | KCNH2KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL6166248 | 0.86 | KCNH2 (0.49) | KCNH2KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL6166243 | 0.86 | KCNH2 (0.49) | KCNH2KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL9550572 | 0.85 | KCNH2 (0.53) | KCNH2KMT2ANPSR1MAPTHTT | |
| SCHEMBL9550576 | 0.85 | KCNH2 (0.53) | KCNH2KMT2ANPSR1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6809114-B2 | ANTIARRHYTHMIC AGENTS; SUCH AS 6-ACETYLAMINO-3,4-DIHYDRO-2,2-DIMETHYL-7-NITRO-4-N-PENTYLAMINO-2H-1 -BENZOPYRAN-3-OL | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2004-10-26 | — | — | US | disclosed |
| US-20040068002-A1 | 4-aminobenzopyran derivatives | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2004-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040068002-A1 | 4-aminobenzopyran derivatives | CYP2D6, KCNH1, CYP2B6 | KCNH2 5/4885HCAR3 604/4885KMT2A 2128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.