Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.37 |
| ▸ | WDR5 | P61964 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1505694 | 0.96 | ANPEP (0.41) | ANPEPPAX8P2RX4WDR5ALDH1A1 | |
| SCHEMBL3384889 | 0.88 | HPRT1 (0.47) | ANPEPPAX8WDR5ALDH1A1CYP2A6 | |
| SCHEMBL6252400 | 0.71 | HSD17B10 (0.35) | ANPEPP2RX4WDR5ALDH1A1CYP2A6 | |
| SCHEMBL28375313 | 0.71 | ALDH1A1 (0.35) | ANPEPP2RX4ALDH1A1CYP2A6TSHR | |
| SCHEMBL9452406 | 0.70 | ANPEP (0.38) | ANPEPPAX8WDR5ALDH1A1CYP2A6 | |
| SCHEMBL28864983 | 0.70 | ALDH1A1 (0.34) | ANPEPP2RX4ALDH1A1CYP2A6TSHR | |
| SCHEMBL4623560 | 0.68 | ALDH1A1 (0.44) | ANPEPPAX8WDR5ALDH1A1CYP2A6 | |
| SCHEMBL29442976 | 0.68 | ALDH1A1 (0.44) | ANPEPPAX8WDR5ALDH1A1CYP2A6 | |
| SCHEMBL994781 | 0.68 | CES1 (0.47) | ANPEPPAX8ALDH1A1CYP2A6TSHR | |
| SCHEMBL9681752 | 0.68 | ANPEP (0.42) | ANPEPPAX8ALDH1A1CYP2A6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1521733-A1 | MODULATORS OF THE GLUCOCORTICOID RECEPTOR | Pfizer Products Inc. (US) | 2005-04-13 | — | — | EP | disclosed |
| WO-2004005229-A1 | MODULATORS OF THE GLUCOCORTICOID RECEPTOR | PFIZER PRODUCTS INC. (US) | 2004-01-15 | — | — | WO | disclosed |