Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 3/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1505694 | 0.91 | ANPEP (0.41) | HPRT1PAX8TDP1ALDH1A1CYP2A6 | |
| Ethylene SCHEMBL6167785 | 0.88 | ANPEP (0.40) | HPRT1PAX8TDP1ALDH1A1LMNA | |
| SCHEMBL7773084 | 0.81 | HPRT1 (0.44) | HPRT1PAX8CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1445153 | 0.74 | HPRT1 (0.52) | HPRT1PAX8CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL30516909 | 0.74 | HPRT1 (0.52) | HPRT1PAX8CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL16337407 | 0.73 | HPRT1 (0.47) | HPRT1PAX8CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL30783256 | 0.73 | HPRT1 (0.47) | HPRT1PAX8CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL19032592 | 0.72 | GSK3A (0.34) | CYP1A2CYP2C9CYP2C19ALDH1A1MEN1 | |
| SCHEMBL7635425 | 0.72 | HPRT1 (0.50) | HPRT1PAX8CYP1A2TDP1ALDH1A1 | |
| SCHEMBL3414799 | 0.71 | HPRT1 (0.48) | HPRT1PAX8CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100068302-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER | TRASLATIONAL CANCER DRUGS PHARMA, S.L. (ES) | 2010-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100068302-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER | ASAH1, ACER2, ASAH2 | HPRT1 981/4885PAX8 4487/4885CYP1A2 3407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.