Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 9/20 | 0.42 |
| ▸ | F2 | P00734 | 6/20 | 0.42 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.38 |
| ▸ | F3 | P13726 | 2/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6168271 | 0.89 | SMN1; SMN2 (0.46) | F10F2TMPRSS6PRSS1ALOX5 | |
| Trifluoroacetic Acid SCHEMBL6165502 | 0.84 | ALOX5 (0.41) | F10F2PRSS1ALOX5PRSS2 | |
| Trifluoroacetic Acid SCHEMBL6163584 | 0.83 | F10 (0.46) | F10F2PRSS1ALOX5F3 | |
| Trifluoroacetic Acid SCHEMBL6164576 | 0.82 | F10 (0.46) | F10F2PRSS1ALOX5F3 | |
| Trifluoroacetic Acid SCHEMBL6166404 | 0.82 | PRSS1 (0.53) | F10F2PRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL6166475 | 0.81 | SMN1; SMN2 (0.53) | F10F2PRSS1ALOX5F3 | |
| Trifluoroacetic Acid SCHEMBL6161730 | 0.81 | MAPT (0.49) | F10F2TMPRSS6PRSS1ALOX5 | |
| Trifluoroacetic Acid SCHEMBL6162234 | 0.80 | SMN1; SMN2 (0.48) | F10F2TMPRSS6PRSS1ALOX5 | |
| Trifluoroacetic Acid SCHEMBL6163059 | 0.80 | SMN1; SMN2 (0.47) | F10F2PRSS1ALOX5F3 | |
| Trifluoroacetic Acid SCHEMBL6165958 | 0.79 | PRSS1 (0.46) | F10F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254136-A4 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG CHEM INVESTMENT LTD (KR) | 2005-06-01 | — | — | EP | disclosed |
| EP-1254136-A1 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG Chem Investment, Ltd. (KR) | 2002-11-06 | — | — | EP | disclosed |
| WO-2001055146-A1 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG CHEM INVESTMENT LTD. (KR) | 2001-08-02 | — | — | WO | disclosed |